Zheng Youxiong, Tang Yan, Yu Jianwei, Xie Lan, Dong Huiyou, Deng Rongsheng, Jia Fuhua, Liu Bingxin, Gao Li, Duan Junyuan
Qinghai Provincial Key Laboratory of New Light Alloys, Qinghai Provincial Engineering Research Center of High Performance Light Metal Alloys and Forming, Qinghai University, Xining 810016, China.
State Key Laboratory of Material Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China.
Materials (Basel). 2020 Jan 16;13(2):440. doi: 10.3390/ma13020440.
Building novel functional nanomaterials with a polymer is one of the most dynamic research fields at present. Here, three amphiphilic block copolymers of 8-hydroxyquinoline derivative motifs (MQ) with excellent coordination function were synthesized by Reversible Addition-Fragmentation Chain Transfer Polymerization (RAFT) polymerization. The coordination micelles were prepared through the self-assembly process, which the MQ motifs were dispersed in the hydrophobic polystyrene (PSt) blocks and hydrophilic Poly(N-isopropylacrylamide (PNIPAM)) blocks, respectively. The dual-emission micelles including the intrinsic red light emission of quantum dots (QDs) and the coordination green light emission of Zn-MQ complexes were built by introducing the CdSe/ZnS and CdTe/ZnS QDs in the core and shell precisely in the coordination micelles through the coordination-driven self-assembly process. Furthermore, based on the principle of three primary colors that produce white light emission, vinyl carbazole units (Polyvinyl Carbazole, PVK) with blue light emission were introduced into the hydrophilic PNIPAM blocks to construct the white light micelles that possess special multi-emission properties in which the intrinsic red light emission of QDs, the coordination green light of Zn-MQ complexes, and the blue light emission of PVK were synergized. The dual and multi-emission hybrid micelles have great application prospects in ratiometric fluorescent probes and biomarkers.
利用聚合物构建新型功能纳米材料是当前最具活力的研究领域之一。在此，通过可逆加成-断裂链转移聚合（RAFT）聚合反应合成了三种具有优异配位功能的8-羟基喹啉衍生物基序（MQ）两亲性嵌段共聚物。通过自组装过程制备配位胶束，其中MQ基序分别分散在疏水的聚苯乙烯（PSt）嵌段和亲水的聚（N-异丙基丙烯酰胺）（PNIPAM）嵌段中。通过配位驱动的自组装过程，将CdSe/ZnS和CdTe/ZnS量子点精确地引入到配位胶束的核和壳中，构建了包括量子点（QDs）的固有红光发射和Zn-MQ配合物的配位绿光发射的双发射胶束。此外，基于产生白光发射的三原色原理，将具有蓝光发射的乙烯基咔唑单元（聚乙烯咔唑，PVK）引入亲水的PNIPAM嵌段中，构建了具有特殊多发射特性的白光胶束，其中量子点的固有红光发射、Zn-MQ配合物的配位绿光和PVK的蓝光发射相互协同。这种双发射和多发射混合胶束在比率荧光探针和生物标志物方面具有巨大的应用前景。
