School of Nursing, Peking University, Beijing, China.
Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.
Obesity (Silver Spring). 2020 Mar;28(3):502-509. doi: 10.1002/oby.22715. Epub 2020 Jan 22.
This meta-analysis aimed to assess the effect of mobile application (app) interventions on weight loss in patients with type 2 diabetes.
Electronic databases were searched for randomized controlled trials examining the use of mobile app interventions with outcomes on weight loss evaluated by body weight or other measures such as BMI or waist circumference. A random-effects model was applied to obtain weight mean differences and 95% CIs.
Fourteen studies enrolling 2,129 patients with type 2 diabetes were included. Mobile app interventions could significantly reduce body weight (weight mean difference, -0.84 kg; 95% CI: -1.51 to -0.17 kg) and lower waist circumference (-1.35 cm; 95% CI: -2.16 to -0.55 cm) but may not decrease BMI (-0.08 kg/m ; 95% CI: -0.41 to 0.25 kg/m ). The reductions appeared to be more pronounced in patients with obesity or among studies using mobile app interventions combined with other behavior components. However, weight loss was not moderated by the functionalities of the mobile apps (all P > 0.05) or by the intervention duration (all P > 0.87).
Mobile app interventions lead to weight loss in patients with type 2 diabetes and are worth recommending for weight loss promotion.
本荟萃分析旨在评估移动应用程序（app）干预措施对 2 型糖尿病患者体重减轻的影响。
检索电子数据库，以寻找评估体重减轻的移动应用程序干预措施的随机对照试验，这些试验使用体重或其他指标（如 BMI 或腰围）来评估体重。采用随机效应模型获得体重均数差值和 95%置信区间。
共纳入 14 项研究，涉及 2129 例 2 型糖尿病患者。移动应用程序干预措施可显著降低体重（体重均数差值，-0.84kg；95%置信区间：-1.51 至 -0.17kg）和腰围（-1.35cm；95%置信区间：-2.16 至 -0.55cm），但可能不会降低 BMI（-0.08kg/m；95%置信区间：-0.41 至 0.25kg/m）。在肥胖患者或在使用移动应用程序干预措施与其他行为成分相结合的研究中，这种降低似乎更为明显。然而，体重减轻未受移动应用程序功能（均 P>0.05）或干预持续时间（均 P>0.87）的调节。
移动应用程序干预措施可导致 2 型糖尿病患者体重减轻，值得推荐用于促进体重减轻。
