使用手机应用程序干预措施促进减肥：荟萃分析。

BACKGROUND: Obesity and lack of physical activity are major health risk factors for many life-threatening diseases, such as cardiovascular diseases, type 2 diabetes, and cancer. The use of mobile app interventions to promote weight loss and boost physical activity among children and adults is fascinating owing to the demand for cutting-edge and more efficient interventions. Previously published studies have examined different types of technology-based interventions and their impact on weight loss and increase in physical activity, but evidence regarding the impact of only a mobile phone app on weight loss and increase in physical activity is still lacking. OBJECTIVE: The main objective of this study was to assess the efficacy of a mobile phone app intervention for reducing body weight and increasing physical activity among children and adults. METHODS: PubMed, Google Scholar, Scopus, EMBASE, and the Web of Science electronic databases were searched for studies published between January 1, 2000, and April 30, 2019, without language restrictions. Two experts independently screened all the titles and abstracts to find the most appropriate studies. To be included, studies had to be either a randomized controlled trial or a case-control study that assessed a mobile phone app intervention with body weight loss and physical activity outcomes. The Cochrane Collaboration Risk of Bias tool was used to examine the risk of publication bias. RESULTS: A total of 12 studies involving a mobile phone app intervention were included in this meta-analysis. Compared with the control group, the use of a mobile phone app was associated with significant changes in body weight (-1.07 kg, 95% CI -1.92 to -0.21, P=.01) and body mass index (-0.45 kg/m2, 95% CI -0.78 to -0.12, P=.008). Moreover, a nonsignificant increase in physical activity was observed (0.17, 95% CI -2.21 to 2.55, P=.88). CONCLUSIONS: The findings of this study demonstrate the promising and emerging efficacy of using mobile phone app interventions for weight loss. Future studies are needed to explore the long-term efficacy of mobile app interventions in larger samples.

背景：肥胖和缺乏身体活动是许多危及生命的疾病的主要健康风险因素，如心血管疾病、2 型糖尿病和癌症。由于对前沿和更有效的干预措施的需求，使用移动应用程序干预来促进儿童和成人减肥和增加身体活动的方法令人着迷。以前发表的研究已经检查了不同类型的基于技术的干预措施及其对减肥和增加身体活动的影响，但关于仅使用移动电话应用程序对减肥和增加身体活动影响的证据仍然缺乏。

目的：本研究的主要目的是评估移动电话应用程序干预在儿童和成人中减肥和增加身体活动的效果。

方法：在 2000 年 1 月 1 日至 2019 年 4 月 30 日期间，没有语言限制地在 PubMed、Google Scholar、Scopus、EMBASE 和 Web of Science 电子数据库中搜索发表的研究。两位专家独立筛选所有标题和摘要，以找到最合适的研究。纳入的研究必须是随机对照试验或病例对照研究，评估移动电话应用程序干预与体重减轻和身体活动结果的关系。使用 Cochrane 协作风险偏倚工具检查发表偏倚的风险。

结果：共有 12 项涉及移动电话应用程序干预的研究纳入了本次荟萃分析。与对照组相比，使用移动电话应用程序与体重（-1.07kg，95%CI-1.92 至-0.21，P=.01）和体重指数（-0.45kg/m2，95%CI-0.78 至-0.12，P=.008）的显著变化相关。此外，观察到身体活动的增加不显著（0.17，95%CI-2.21 至 2.55，P=.88）。

结论：本研究的结果表明，使用移动电话应用程序干预减肥具有有前途和新兴的效果。需要进一步的研究来探索更大样本中移动应用程序干预的长期效果。