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与龈下刮治术相比,入路瓣手术治疗牙周炎的疗效:一项系统评价和荟萃分析。

Efficacy of access flap procedures compared to subgingival debridement in the treatment of periodontitis. A systematic review and meta-analysis.

作者信息

Sanz-Sánchez Ignacio, Montero Eduardo, Citterio Filippo, Romano Federica, Molina Ana, Aimetti Mario

机构信息

Etiology and Therapy of Periodontal Diseases (ETEP) Research Group, University Complutense, Madrid, Spain.

Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy.

出版信息

J Clin Periodontol. 2020 Jul;47 Suppl 22:282-302. doi: 10.1111/jcpe.13259.

Abstract

AIM

This systematic review aimed to answer the following focused questions: (a) "In patients with periodontitis, how effective are access flaps (AFs) as compared to subgingival debridement in attaining probing depth (PD) reduction?" and (b) "In patients with periodontitis, does the type of AF impact PD reduction?".

MATERIAL AND METHODS

Randomized clinical trials were searched in three databases. Besides PD, information concerning clinical attachment level (CAL) and other relevant outcomes was also collected. Meta-analyses were performed whenever possible and results were categorized based on the initial PD.

RESULTS

Thirty-six publications were included. AFs resulted in a significantly greater PD reduction in deep pockets (>6 mm or ≥6 mm), as compared to subgingival debridement, in short- (n = 4; weighted mean difference [WMD] = 0.67 mm; 95% confidence interval [CI] 0.37,0.97; p < .001) and long-term studies (n = 4; WMD = 0.39 mm; 95% CI 0.09,0.70; p = .012), while in moderately deep pockets (4-6, 5-6 or 4-5 mm) only in short-term studies (n = 4; WMD = 0.34; 95% CI 0.21,0.46; p < .001). In shallow pockets (1-3 or 1-4 mm), AFs led to greater CAL (n = 7; WMD = -0.43 mm; 95% CI -0.56, -0.28; p < .001). There was not enough evidence to answer question PICO 2.

CONCLUSIONS

AFs resulted in greater PD reduction in the treatment of deep and moderate pockets.

摘要

目的

本系统评价旨在回答以下重点问题:(a)“在牙周炎患者中,与龈下刮治相比,翻瓣术(AFs)在降低探诊深度(PD)方面的效果如何?”以及(b)“在牙周炎患者中,AFs的类型是否会影响PD降低?”

材料与方法

在三个数据库中检索随机临床试验。除了PD外,还收集了有关临床附着水平(CAL)和其他相关结果的信息。尽可能进行荟萃分析,并根据初始PD对结果进行分类。

结果

纳入36篇出版物。与龈下刮治相比,在短期(n = 4;加权平均差[WMD]=0.67mm;95%置信区间[CI]0.37,0.97;p <.001)和长期研究(n = 4;WMD = 0.39mm;95%CI 0.09,0.70;p = 0.012)中,AFs在深牙周袋(>6mm或≥6mm)中导致PD降低更为显著,而在中度深牙周袋(4 - 6、5 - 6或4 - 5mm)中仅在短期研究中有显著差异(n = 4;WMD = 0.34;95%CI 0.21,0.46;p <.001)。在浅牙周袋(1 - 3或1 - 4mm)中,AFs导致更大的CAL(n = 7;WMD = -0.43mm;95%CI -0.56,-0.28;p <.001)。没有足够的证据回答问题PICO 2。

结论

AFs在治疗深和中度牙周袋时能更显著地降低PD。

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