Division of Infectious Diseases.
Division of Cardiology, Department of Internal Medicine.
Am J Med. 2020 Sep;133(9):1101-1104. doi: 10.1016/j.amjmed.2019.12.019. Epub 2020 Jan 21.
Coronary catheterization with angiography is often performed prior to surgical valve replacement in infectious endocarditis. There are no existing data as to whether this intervention is clinically necessary or leads to a change in surgical management. In order to determine the frequency with which coronary angiography impacts surgical management in infectious endocarditis, we conducted a retrospective review of surgically managed endocarditis cases at a tertiary care medical center.
Utilizing the institutional Society of Thoracic Surgeon's database, we identified 598 patients with surgically managed endocarditis between April 29, 2011 and December 31, 2018. Patient variables were recorded, including risk factors for coronary artery disease, whether the patient received coronary angiography prior to surgery, and if the patient underwent coronary artery bypass grafting as part of their valve surgery.
There were 430 patients who received coronary catheterization with angiography prior to surgical valve replacement for infectious endocarditis, and 168 patients proceeded to surgery without coronary angiography. Nine percent of patients underwent coronary artery bypass grafting at the time of valve replacement as a result of coronary angiography findings. There was no significant difference in 30-day mortality for patients with endocarditis who underwent coronary angiography when compared with those who did not receive coronary angiography (2.6 vs 2.4%; P = 0.89).
Left heart catheterization with coronary angiography prior to surgical valve replacement leads to coronary artery bypass grafting in the minority of infective endocarditis patients.
在感染性心内膜炎患者进行外科瓣膜置换术前,通常会进行冠状动脉造影检查。目前尚无数据表明该介入治疗在临床上是否必要,或是否会改变手术治疗策略。为了明确冠状动脉造影检查在感染性心内膜炎手术治疗中的影响频率,我们对一家三级医疗中心接受外科治疗的心内膜炎病例进行了回顾性研究。
利用机构胸外科医生协会数据库,我们确定了 2011 年 4 月 29 日至 2018 年 12 月 31 日期间 598 例接受外科治疗的心内膜炎患者。记录患者的变量,包括冠状动脉疾病的危险因素、患者术前是否接受冠状动脉造影检查,以及患者是否在瓣膜手术中接受冠状动脉旁路移植术。
有 430 例感染性心内膜炎患者在外科瓣膜置换术前接受了冠状动脉造影检查,168 例患者在未接受冠状动脉造影检查的情况下接受了手术。由于冠状动脉造影检查结果,有 9%的患者在瓣膜置换时接受了冠状动脉旁路移植术。与未接受冠状动脉造影检查的患者相比,接受冠状动脉造影检查的患者的 30 天死亡率没有显著差异(2.6%比 2.4%;P=0.89)。
在外科瓣膜置换术前进行左心导管检查和冠状动脉造影检查,仅少数感染性心内膜炎患者需要进行冠状动脉旁路移植术。