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人工泪液溶液对 、 、 、 接触镜的附着作用。

Adhesion of , , , to contact lenses under the influence of an artificial tear solution.

机构信息

Centre for Ocular Research & Education, School of Optometry & Vision Science, University of Waterloo, Waterloo, Canada.

出版信息

Biofouling. 2020 Jan;36(1):32-43. doi: 10.1080/08927014.2019.1710832. Epub 2020 Jan 23.

Abstract

Corneal infection is a devastating sight-threatening complication that is associated with contact lens (CL) wear, commonly caused by . Lately, , , and have been associated with corneal infection. This study investigated the adhesion of these emerging pathogens to CLs, under the influence of an artificial tear solution (ATS) containing a variety of components commonly found in human tears. Two different CL materials, etafilcon A and senofilcon A, either soaked in an ATS or phosphate buffered saline, were exposed to the bacteria. Bacterial adhesion was investigated using a radio-labeling technique (total counts) and plate count method (viable counts). The findings from this study revealed that in addition to , among the emerging pathogens evaluated, showed an increased propensity for adherence to both CL materials and showed lower viability. ATS influenced the viable counts more than the total counts on CLs.

摘要

角膜感染是一种破坏性的视力威胁并发症,与隐形眼镜(CL)佩戴有关,通常由 引起。最近, 、 、 和 与角膜感染有关。本研究调查了这些新兴病原体在含有各种常见于人泪液成分的人工泪液溶液(ATS)的影响下对 CL 的粘附。两种不同的 CL 材料,即 etafilcon A 和 senofilcon A,无论是浸泡在 ATS 还是磷酸盐缓冲盐水中,都暴露于细菌中。使用放射性标记技术(总计数)和平板计数法(活菌计数)研究细菌粘附。这项研究的结果表明,除了 之外,在所评估的新兴病原体中, 对两种 CL 材料的粘附倾向增加,而 显示出较低的存活率。ATS 对 CL 上的活菌计数的影响大于总计数。

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