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[输血对结直肠癌肿瘤复发及生存率的影响]

[Effect of blood transfusion on tumor recurrence and rate of survival in colorectal cancer].

作者信息

Wirsching R P, Demmel N, Liewald F, Mempel W, Zwingers N

机构信息

Chirurgische Klinik, Ludwig-Maximilians-Universität München, Klinikum Grosshadern.

出版信息

Chirurg. 1988 Oct;59(10):647-53.

PMID:3197463
Abstract

In 439 curatively resected colorectal cancer patients determinants for homologous blood transfusion and its influence on postoperative and long-term results were evaluated. The rate of transfusion was significantly higher in women, rectal cancers, large tumors, advanced pT-stage and extended resections but not in tumor-stenosis, lower graded tumors, advanced Dukes-stage or less experienced surgeons. Transfused patients showed significantly more postoperative complications, higher recurrence rates as well as less favorable long-term survival. Homologous blood transfusions are correlated with survival rates.

摘要

对439例接受根治性切除的结直肠癌患者,评估了同源输血的决定因素及其对术后和长期结果的影响。女性、直肠癌、大肿瘤、pT分期较晚和扩大切除患者的输血率显著更高,但肿瘤狭窄、低分级肿瘤、Dukes分期较晚或经验较少的外科医生的患者输血率并非如此。接受输血的患者术后并发症显著更多、复发率更高且长期生存率更不理想。同源输血与生存率相关。

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