18F-FDG 和 68Ga-替曲膦 PET/CT 揭示同时患有滤泡性淋巴瘤的 POEMS 综合征经治疗后情况
Posttreated POEMS Syndrome With Concurrent Follicular Lymphoma Revealed by 18F-FDG and 68Ga-Pentixafor PET/CT.
机构信息
Department of Hematology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China.
出版信息
Clin Nucl Med. 2020 Mar;45(3):220-222. doi: 10.1097/RLU.0000000000002923.
A 59-year-old man with history of POEMS syndrome was found with a painless mass in the right neck for 9 months. In F-FDG and Ga-pentixafor PET/CT, there were multiple neck nodes and left inguinal nodes that showed intense F-FDG and Ga-pentixafor uptake. In addition, osteoblastic bone lesions with mild F-FDG and Ga-pentixafor uptake were noted in the pelvis, which was consistent with posttreated osseous involvement of POEMS syndrome. However, considering lymphoadenopathy with such intense F-FDG uptake is not usually seen in POEMS syndrome, the patient underwent biopsy of the right cervical nodes. The histopathology with immunohistochemistry confirmed follicular lymphoma.
一位 59 岁男性，患有 POEMS 综合征病史，发现右侧颈部无痛性肿块 9 个月。在 F-FDG 和 Ga-戊基肟 PET/CT 中，多个颈部淋巴结和左侧腹股沟淋巴结显示出强烈的 F-FDG 和 Ga-戊基肟摄取。此外，骨盆中还可见成骨性骨病变，伴有轻度 F-FDG 和 Ga-戊基肟摄取，与 POEMS 综合征治疗后的骨受累一致。然而，鉴于 POEMS 综合征中通常不会出现如此强烈的 F-FDG 摄取的淋巴结病，该患者接受了右侧颈部淋巴结活检。组织病理学检查结合免疫组化证实为滤泡性淋巴瘤。
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