Department of Pediatric Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
The Committee on the NCD, The Japanese Society of Pediatric Surgeons, Tokyo, Japan.
Ann Surg. 2021 Dec 1;274(6):e599-e604. doi: 10.1097/SLA.0000000000003804.
The aim of the study was to investigate the effect of abdominal drainage at appendectomy for complicated appendicitis in children.
Although an abdominal drain placement at appendectomy is an option for reducing or preventing postoperative infectious complication, there is controversy regarding its effect for complicated appendicitis.
The study used the data on appendectomies for complicated appendicitis in children (≤15 years old) that were operated in 2015 and registered in the National Clinical Database, a nationwide surgical database in Japan. One-to-two propensity score matching was performed to compare postoperative outcomes between patients with and without drainage at appendectomy.
The study included 1762 pediatric appendectomies for complicated appendicitis, 458 of which underwent abdominal drainage at appendectomy. In the propensity-matched analysis, the drainage group showed a significant increase in wound dehiscence [drain (-) vs drain (+); 0.3% vs 2.4%, P = 0.001], and postoperative hospital stay (median: 7 days vs 9 days, P < 0.001). There were no significant differences in the incidence of any complications, organ space surgical site infection, re-admission, and reoperation.Subgroup analyses in perforated appendicitis and perforated appendicitis with abscess, and open and laparoscopic appendectomy all demonstrated that drain placement was not associated with a reduction in any complication or organ space surgical site infection. However, it was significantly associated with longer hospital stays.
This study suggested that an abdominal drain placement at appendectomy for complicated appendicitis among children has no advantage and can be harmful for preventing postoperative complications.
本研究旨在探讨阑尾切除术治疗儿童复杂性阑尾炎时放置腹腔引流的效果。
尽管在阑尾切除术中放置腹腔引流是减少或预防术后感染性并发症的一种选择,但对于复杂性阑尾炎,其效果仍存在争议。
本研究使用了日本全国外科数据库(National Clinical Database)中 2015 年登记的儿童(≤15 岁)复杂性阑尾炎阑尾切除术的数据。采用 1:2 倾向评分匹配比较阑尾切除术中有无引流患者的术后结局。
本研究共纳入 1762 例儿童复杂性阑尾炎阑尾切除术,其中 458 例行腹腔引流。在倾向评分匹配分析中,引流组的切口裂开发生率(引流(-)vs 引流(+);0.3% vs 2.4%,P = 0.001)和术后住院时间(中位数:7 天 vs 9 天,P < 0.001)显著增加。两组在任何并发症、器官间隙手术部位感染、再入院和再次手术的发生率方面无显著差异。穿孔性阑尾炎和穿孔性阑尾炎合并脓肿、开腹和腹腔镜阑尾切除术的亚组分析均表明,引流放置与任何并发症或器官间隙手术部位感染的减少均无关,但与较长的住院时间显著相关。
本研究表明,儿童复杂性阑尾炎阑尾切除术中放置腹腔引流并无优势,反而可能对预防术后并发症有害。