Odahara Masaki
Biomacromolecules Research Team, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan.
Plants (Basel). 2020 Jan 23;9(2):145. doi: 10.3390/plants9020145.
Organelle genomes are essential for plants; however, the mechanisms underlying the maintenance of organelle genomes are incompletely understood. Using the basal land plant as a model, nuclear-encoded homologs of bacterial-type homologous recombination repair (HRR) factors have been shown to play an important role in the maintenance of organelle genome stability by suppressing recombination between short dispersed repeats. In this review, I summarize the factors and pathways involved in the maintenance of genome stability, as well as the repeats that cause genomic instability in organelles in , and compare them with findings in other plant species. I also discuss the relationship between HRR factors and organelle genome structure from the evolutionary standpoint.
细胞器基因组对植物至关重要；然而，维持细胞器基因组的潜在机制尚未完全明确。以基部陆地植物为模型，已表明细菌型同源重组修复（HRR）因子的核编码同源物通过抑制短分散重复序列之间的重组，在维持细胞器基因组稳定性方面发挥重要作用。在这篇综述中，我总结了参与维持基因组稳定性的因子和途径，以及在基部陆地植物中导致细胞器基因组不稳定的重复序列，并将它们与其他植物物种的研究结果进行比较。我还从进化的角度讨论了HRR因子与细胞器基因组结构之间的关系。
