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腘绳肌周围注射或前闭孔神经阻滞联合内收肌管阻滞对前交叉韧带重建术后镇痛效果的影响:一项随机对照试验。

Effect of combining peri-hamstring injection or anterior obturator nerve block on the analgesic efficacy of adductor canal block for anterior cruciate ligament reconstruction: a randomised controlled trial.

机构信息

Department of Anaesthesia and Perioperative Medicine, Royal Victoria Hospital, Belfast Trust, Belfast, UK.

Department of Anesthesia, University of Iowa, Iowa City, IA, USA.

出版信息

Br J Anaesth. 2020 Mar;124(3):299-307. doi: 10.1016/j.bja.2019.11.032. Epub 2020 Jan 21.

Abstract

BACKGROUND

Pain after anterior cruciate ligament reconstruction (ACLR) with autologous hamstring graft can be attributed to both arthroscopic surgery and the graft donor site. This study investigated whether donor site pain control was superior with the addition of either peri-hamstring injection or anterior division obturator nerve block in comparison with adductor canal block (ACB) alone.

METHODS

Patients scheduled to undergo knee arthroscopy with ACLR using a graft from the ipsilateral hamstring were randomised to one of three groups. All patients received ACB and multimodal analgesia. Subjects in Group H received peri-hamstring local anaesthetic injection while subjects in Group O received an anterior division of the obturator nerve block, and subjects in Group C served as a control group (ACB alone).

RESULTS

In 105 subjects undergoing ACLR, there was no significant difference between groups H, O, and C for the primary outcome of pain on movement as assessed by numerical rating scale (NRS) on knee flexion at 2 h after operation (P=0.11). There was no difference in NRS at any time point in the first 48 h after operation, nor was there a difference in oxycodone consumption between the three groups at 24 h (P=0.2). Worst knee pain was initially at the graft donor site in all three groups, which transitioned to anterior knee pain after 12 h.

CONCLUSIONS

The addition of ultrasound-guided peri-hamstring injection or anterior division of obturator nerve block to ACB did not result in a significant reduction in pain or opioid consumption after ACLR with ipsilateral hamstring graft.

CLINICAL TRIAL REGISTRATION

NCT01868282.

摘要

背景

前交叉韧带重建(ACLR)后出现的疼痛可归因于关节镜手术和移植物供体部位。本研究旨在探讨与单独使用收肌管阻滞(ACB)相比,在 ACB 中加入腘绳肌周围注射或前分支闭孔神经阻滞是否能更好地控制供体部位疼痛。

方法

计划接受同侧腘绳肌腱 ACLR 的膝关节镜手术的患者被随机分为三组。所有患者均接受 ACB 和多模式镇痛。H 组患者接受腘绳肌周围局部麻醉注射,O 组患者接受闭孔神经前分支阻滞,C 组患者作为对照组(仅接受 ACB)。

结果

在 105 例行 ACLR 的患者中,H、O 和 C 组在术后 2 小时膝关节屈曲时用数字评分量表(NRS)评估的运动疼痛的主要结局(P=0.11)之间无显著差异。在术后 48 小时内的任何时间点,NRS 均无差异,三组在 24 小时时的羟考酮消耗量也无差异(P=0.2)。最初三组的膝关节疼痛均发生在移植物供体部位,12 小时后转为前膝关节疼痛。

结论

在使用同侧腘绳肌腱进行 ACLR 中,与单独使用 ACB 相比,在 ACB 中加入超声引导下的腘绳肌周围注射或前分支闭孔神经阻滞并不能显著减轻疼痛或减少阿片类药物的消耗。

临床试验注册号

NCT01868282。

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