Servicio de Cardiología, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, Spain.
Fundación Instituto para la Mejora de la Asistencia Sanitaria, Madrid, Spain.
Rev Esp Cardiol (Engl Ed). 2020 Jun;73(6):488-494. doi: 10.1016/j.rec.2019.08.016. Epub 2020 Jan 21.
To analyze the association between volume and outcomes in coronary artery bypass grafting (CABG) in the Spanish National Health System.
We analyzed CABG episodes from 2013 to 2015. The selected outcome variables were in-hospital mortality in the index episode, 30-day cardiac-related readmissions, and mortality during readmission. Risk-adjusted rates of in-hospital mortality (RAMR) and 30-day readmissions (RARR) were calculated using multilevel logistic regression. High- and low-volume hospitals for CABG were identified by a nonconditioned analysis (k-means) and by compliance with the volume recommendation of clinical practice guidelines.
A total of 17 335 CABG index episodes were included, with a crude in-hospital mortality rate of 5.0%. Episodes attended in low-volume centers for CABG (< 155 CABG per year) showed 17% higher RAMR (5.81%±2.07% vs 4.96%±1.76%; P <.001) and a negative linear correlation between volume and RARR (r=-0.318; P=.029), as well as a higher percentage of complications during the episode. The same association between volume and more favorable outcomes was found in isolated CABG.
The mean CABG volume is low in Spanish National Health System hospitals. Higher volume was associated with better outcomes in CABG, both total and isolated. The findings of this study indicate the need for a higher concentration of CABG programs, as well as the publication of risk-adjusted outcomes of coronary intervention.
分析西班牙国家卫生系统中冠状动脉旁路移植术(CABG)的量与结局之间的关联。
我们分析了 2013 年至 2015 年的 CABG 病例。选择的结局变量包括索引病例的院内死亡率、30 天心脏相关再入院率和再入院期间的死亡率。使用多水平逻辑回归计算风险调整后的院内死亡率(RAMR)和 30 天再入院率(RARR)。通过非条件分析(k-均值)和符合临床实践指南的容量推荐来确定 CABG 的高容量和低容量医院。
共纳入 17335 例 CABG 索引病例,住院死亡率为 5.0%。在 CABG 低容量中心(每年<155 例 CABG)就诊的病例,RAMR 高出 17%(5.81%±2.07%比 4.96%±1.76%;P<.001),且 RARR 与容量呈负线性相关(r=-0.318;P=.029),同时在该病例中发生并发症的比例更高。在单纯 CABG 中也发现了容量与更好结局之间的这种关联。
西班牙国家卫生系统医院的平均 CABG 容量较低。更高的容量与 CABG 总例数和单纯 CABG 的更好结局相关。本研究结果表明需要更高浓度的 CABG 计划,以及公布冠状动脉介入术的风险调整结局。