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联合可变免疫缺陷中外源胰岛素抗体综合征的治疗性血浆置换：病例报告。

Therapeutic plasma exchange for exogenous insulin antibody syndrome in combined variable immunodeficiency: a case report.

机构信息

Department of Pathology and Laboratory Medicine, University of Wisconsin Hospital and Clinics, Madison, WI.

Department of Anesthesiology, University of Wisconsin Hospital and Clinics, Madison, WI.

出版信息

J Clin Apher. 2020 Apr;35(2):128-130. doi: 10.1002/jca.21769. Epub 2020 Jan 25.

DOI:10.1002/jca.21769
PMID:31981239
Abstract

A 32-year-old male with type I diabetes presented with profound hypoglycemia due to exogenous insulin antibody syndrome in the setting of newly-diagnosed common variable immunodeficiency. Immunomodulatory therapy was not initially effective, but after the initiation of plasma exchange hypoglycemia resolved, and glucose lability improved.

摘要

一位 32 岁男性，患有 I 型糖尿病，因新发普通变异性免疫缺陷症导致外源性胰岛素抗体综合征而出现严重低血糖。免疫调节治疗最初无效，但开始血浆置换后低血糖得到缓解，血糖波动得到改善。

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Therapeutic plasma exchange for exogenous insulin antibody syndrome in combined variable immunodeficiency: a case report.联合可变免疫缺陷中外源胰岛素抗体综合征的治疗性血浆置换：病例报告。
J Clin Apher. 2020 Apr;35(2):128-130. doi: 10.1002/jca.21769. Epub 2020 Jan 25.
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Therapeutic plasma exchange normalizes insulin-mediated response in a child with type 1 diabetes and insulin autoimmune syndrome.治疗性血浆置换可使 1 型糖尿病伴胰岛素自身免疫综合征患儿的胰岛素介导反应恢复正常。
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引用本文的文献

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Exogenous Insulin Antibody Syndrome in Patients with Type 2 Diabetes.2型糖尿病患者的外源性胰岛素抗体综合征
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Type 1 diabetes complicated with cyclic vomiting syndrome and exogenous insulin antibody syndrome: A case report.1 型糖尿病合并周期性呕吐综合征和外源性胰岛素抗体综合征：病例报告。
Front Endocrinol (Lausanne). 2022 Nov 10;13:1043301. doi: 10.3389/fendo.2022.1043301. eCollection 2022.
3
Exogenous insulin antibody syndrome treated with plasma exchange after an incomplete response to immunosuppressive therapy.
免疫抑制治疗反应不完全后采用血浆置换治疗外源性胰岛素抗体综合征。
J Clin Apher. 2021 Aug;36(4):664-667. doi: 10.1002/jca.21905. Epub 2021 May 20.
4
Clinical and Laboratory Aspects of Insulin Autoantibody-Mediated Glycaemic Dysregulation and Hyperinsulinaemic Hypoglycaemia: Insulin Autoimmune Syndrome and Exogenous Insulin Antibody Syndrome.胰岛素自身抗体介导的血糖失调和高胰岛素血症性低血糖的临床与实验室特征：胰岛素自身免疫综合征和外源性胰岛素抗体综合征
Clin Biochem Rev. 2020 Dec;41(3):93-102. doi: 10.33176/AACB-20-00008.