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通过改良的德尔菲法就家庭输液中心静脉导管相关血流感染监测定义达成共识。

Reaching consensus on a home infusion central line-associated bloodstream infection surveillance definition via a modified Delphi approach.

作者信息

Keller Sara, Salinas Alejandra, Williams Deborah, McGoldrick Mary, Gorski Lisa, Alexander Mary, Norris Anne, Charron Jennifer, Stienecker Roger Scott, Passaretti Catherine, Maragakis Lisa, Cosgrove Sara E

机构信息

Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD.

Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD.

出版信息

Am J Infect Control. 2020 Sep;48(9):993-1000. doi: 10.1016/j.ajic.2019.12.015. Epub 2020 Jan 23.

Abstract

BACKGROUND

A consensus on a central line-associated bloodstream infection (CLABSI) surveillance definition in home infusion is needed to standardize measurement and benchmark CLABSI to provide data to drive improvement initiatives METHODS: Experts across fields including home infusion therapy, infectious diseases, and healthcare epidemiology convened to perform a 3-step modified Delphi approach to obtain input and achieve consensus on a candidate home infusion CLABSI definition.

RESULTS

The numerator criterion was identified by participants as involving one of the 2 following: (1) recognized pathogen isolated from blood culture and pathogen is not related to infection at another site, or (2) one of the following signs or symptoms: fever of 38°C (100.4°F), chills, or hypotension (systolic blood pressure ≤90 mm Hg), and one of the 2 following: (A) common skin contaminant isolated from 2 blood cultures drawn on separate occasions and organism is not related to infection at another site, or (B) common skin contaminant isolated from blood culture from patient with intravascular access device and provider institutes appropriate antimicrobial therapy. The criteria for a denominator included days from the day of admission with a central venous catheter to day of removal of central venous catheter. In addition, 11 inclusion criteria and 4 exclusion criteria were included.

DISCUSSION

Home infusion therapy and healthcare epidemiology experts developed candidate criteria for a home infusion CLABSI surveillance definition.

CONCLUSIONS

Home care and home infusion agencies can use this definition to monitor their own CLABSI rates and implement preventative strategies.

摘要

背景

需要就家庭输液中中心静脉导管相关血流感染(CLABSI)的监测定义达成共识,以规范测量并将CLABSI作为基准,从而提供数据以推动改进措施。方法:来自家庭输液治疗、传染病和医疗保健流行病学等领域的专家齐聚一堂,采用三步改良德尔菲法,以获取意见并就家庭输液CLABSI候选定义达成共识。

结果

参与者确定分子标准涉及以下两种情况之一:(1)从血培养中分离出的公认病原体,且该病原体与其他部位的感染无关;或(2)以下体征或症状之一:体温38°C(100.4°F)、寒战或低血压(收缩压≤90 mmHg),以及以下两种情况之一:(A)在不同时间采集的两份血培养中分离出常见皮肤污染物,且该微生物与其他部位的感染无关;或(B)从有血管内通路装置的患者血培养中分离出常见皮肤污染物,且医疗服务提供者开始适当的抗菌治疗。分母标准包括从中心静脉导管置入日到拔除日的天数。此外,还包括11条纳入标准和4条排除标准。

讨论

家庭输液治疗和医疗保健流行病学专家制定了家庭输液CLABSI监测定义的候选标准。

结论

家庭护理和家庭输液机构可以使用此定义来监测自身的CLABSI发生率并实施预防策略。

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