Jankowiak R, Cooper R S, Zamzow D, Small G J, Doskocil G, Jeffrey A M
Ames Laboratory, Department of Energy, Iowa State University.
IARC Sci Publ. 1988(89):372-7.
Fluorescence line narrowing (FLN), is a method by which highly characteristic spectra have been obtained for a large number of polycyclic aromatic hydrocarbon (PAH)-DNA adducts and is well suited for the analysis of exposures to complex mixtures of PHA. The basic method is described and recent improvements discussed which overcome one of the major limitations of the method to its wider application to biological samples, that is its sensitivity.
荧光谱线变窄（FLN）是一种方法，通过该方法已获得大量多环芳烃（PAH）-DNA加合物的高度特征性光谱，非常适合用于分析多环芳烃复杂混合物的暴露情况。本文描述了基本方法，并讨论了最近的改进，这些改进克服了该方法在更广泛应用于生物样品时的主要限制之一，即其灵敏度。
