The American British Cowdray Medical Center, Mexico City, Mexico.
Instituto Nacional de Neurología y Neurocirugía, Mexico City, Mexico.
Mult Scler Relat Disord. 2020 May;40:101938. doi: 10.1016/j.msard.2020.101938. Epub 2020 Jan 16.
We present the clinical and imaging characteristics of a patient whom presented with rebound syndrome after switching from fingolimod to cladribine treatment due to hematologic toxicity. Previous imaging studies had shown a non-aggressive phenotype of the disease, however multiple active tumefactive lesions became evident after beginning treatment with cladribine. The patient responded well to plasmapheresis.
我们介绍了一位患者的临床和影像学特征,该患者因血液学毒性而从芬戈莫德转换为克拉屈滨治疗后出现反弹综合征。先前的影像学研究显示疾病具有非侵袭性表型,但开始用克拉屈滨治疗后,多个活跃的肿块样病变变得明显。该患者对血浆置换反应良好。