Suszek Dorota, Majdan Maria, Widłak Karolina, Radulska Joanna, Sowa Klaudia, Stryjecka Ewa, Szuster Aleksandra, Tyburek Justyna, Zalewska Daria
Katedra i Klinika Reumatologii i Układowych Chorób Tkanki Łącznej, Uniwersytet Medyczny, Lublin, Polska
Koło Reumatologiczne Przy Katedrze i Klinice Reumatologii i Układowych Chorób Tkanki Łącznej, Uniwersytet Medyczny, Lublin, Polska
Wiad Lek. 2019 Oct 31;72(10):2010-2016.
Systemic vasculitis is a group of diseases manifested by symptoms from many organs. ANCA-associated vasculitis (AAV) require chronic and often aggressive immunosuppressive treatment. This treatment should be adapted to the disease activity. Assessment of AAV is based on various disease activity questionnaires which contain clinical symptoms of the disease and lab results. The most useful questionnaire is BVAS version 3 (Birmingham Vasculitis Activity Score). In every patients, distinction between activity of AAV and irreversible damage is needed. ANCA antibodies are a predictor of poor prognosis in some patients. Using of these antibodies in monitoring of AAV activity has got minor importance.
系统性血管炎是一组由多个器官出现症状所表现的疾病。抗中性粒细胞胞浆抗体相关性血管炎（AAV）需要长期且通常积极的免疫抑制治疗。这种治疗应根据疾病活动情况进行调整。AAV的评估基于各种疾病活动问卷，这些问卷包含疾病的临床症状和实验室检查结果。最有用的问卷是BVAS第3版（伯明翰血管炎活动评分）。对于每一位患者，都需要区分AAV的活动情况和不可逆损伤。在一些患者中，抗中性粒细胞胞浆抗体是预后不良的预测指标。在监测AAV活动中使用这些抗体的重要性较小。
