Department of Psychiatry, The Jikei University School of Medicine, Tokyo, Japan.
Department of Psychiatry, The Jikei University School of Medicine, Chiba, Japan.
Clin Gerontol. 2022 May-Jun;45(3):673-680. doi: 10.1080/07317115.2020.1720884. Epub 2020 Jan 26.
: We examined the clinicodemographic and psychosocial factors that relate to the presentation and severity of delusions of theft among female patients with amnestic mild cognitive impairment (a-MCI) and Alzheimer's disease (AD).: We enrolled a total of 177 female patients with a-MCI or AD, of whom 40 presented with delusions of theft. We compared the differences in clinicodemographic and psychosocial factors of the 40 patients (delusions of theft group) with 50 age- and Mini-Mental State Examination (MMSE)-matched controls without delusions (control group). Furthermore, we identified the factors associated with the presentation of delusions of theft using a general linear model (GLM). The severity of delusions of theft was calculated using the Neuropsychiatric Inventory Questionnaire, and correlations between the clinicodemographic and psychosocial factors were examined.: Between the two groups, the delusions of theft group had lower scores on the Physical Self-Maintenance Scale and instrumental activities of daily living (IADL) and higher scores on the Japanese version of the Zarit Caregiver Burden Interview (ZBI-J) than the control group. GLM analysis revealed that the IADL score was related to the presentation of delusions of theft. The severity of delusions of theft correlated with the MMSE and the ZBI-J scores in the delusions of theft group.: The two groups had several differences regarding clinicodemographic and psychosocial factors. Furthermore, lower IADL scores were related to symptom presentation. Symptom severity correlated with cognitive functioning and caregiver burden.: In the determination of treatment or care, differences in these factors should be considered.
我们研究了与女性遗忘型轻度认知障碍（a-MCI）和阿尔茨海默病（AD）患者偷窃妄想的表现和严重程度相关的临床人口统计学和心理社会因素。
我们共纳入了 177 名女性 a-MCI 或 AD 患者，其中 40 名患者存在偷窃妄想。我们比较了 40 名有偷窃妄想的患者（妄想组）与 50 名年龄和简易精神状态检查（MMSE）匹配且无妄想的患者（对照组）在临床人口统计学和心理社会因素方面的差异。此外，我们使用一般线性模型（GLM）确定了与偷窃妄想表现相关的因素。使用神经精神病学问卷评估了偷窃妄想的严重程度，并检查了临床人口统计学和心理社会因素之间的相关性。
在两组患者中，妄想组在身体自我维护量表和日常生活活动工具性部分的得分较低，而在日本版照顾者负担量表（ZBI-J）的得分较高。GLM 分析显示，日常生活活动工具性部分得分与偷窃妄想的表现有关。在有偷窃妄想的组中，偷窃妄想的严重程度与 MMSE 和 ZBI-J 评分相关。
两组患者在临床人口统计学和心理社会因素方面存在一些差异。此外，较低的日常生活活动工具性部分得分与症状表现有关。症状严重程度与认知功能和照顾者负担相关。
在确定治疗或护理方案时，应考虑这些因素的差异。
