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沙特儿童和青少年肥胖与心血管危险因素的关系。

Relationship between pediatric adiposity and cardiovascular risk factors in Saudi children and adolescents.

机构信息

Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; Elemental Spectroscopy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

出版信息

Arch Pediatr. 2020 Apr;27(3):135-139. doi: 10.1016/j.arcped.2019.12.007. Epub 2020 Jan 23.

DOI:10.1016/j.arcped.2019.12.007
PMID:31983539
Abstract

BACKGROUND

The etiology of childhood obesity is growing at alarming rates in developed and developing countries. The aim of the present study was to investigate the prevalence of cardiovascular risk factors (hypertension, dyslipidemia, and hyperglycemia) in a sample of Saudi children and to assess their association with different measures of body adiposity.

METHODS

A cross-sectional study was conducted of 200 Saudi children, who were randomly selected from the pediatric clinics at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Anthropometric variables were measured for all study subjects. Fasting blood samples were collected for measurement of blood glucose, insulin, and lipid profile.

RESULTS

Almost half of the study population was overweight and one tenth was obese according to body mass index levels, irrespective of sex. The prevalence of central obesity was higher using the waist-height ratio as opposed to waist circumference and this was true for both sexes. Significantly higher means levels of glucose, insulin, and lipids (P<0.0001 in all) were seen among overweight and obese children than their lean counterparts. All obesity measures in children were significantly associated with cardiovascular risk factors.

CONCLUSION

The severity of overall and abdominal obesity in Saudi children is associated with a higher prevalence of cardiovascular risk factors, with the relationship strength varying by sex.

摘要

背景

在发达国家和发展中国家,儿童肥胖的病因发病率正在以惊人的速度增长。本研究的目的是调查沙特儿童心血管危险因素(高血压、血脂异常和高血糖)的流行情况,并评估其与不同身体肥胖测量指标的相关性。

方法

对 200 名沙特儿童进行了横断面研究,这些儿童是从沙特阿拉伯吉达的阿卜杜勒阿齐兹国王大学医院的儿科诊所中随机选择的。对所有研究对象进行了人体测量变量的测量。采集空腹血样,用于测量血糖、胰岛素和血脂谱。

结果

根据体重指数水平,近一半的研究人群超重,十分之一的儿童肥胖,无论性别如何。与腰围相比,使用腰高比来衡量中心性肥胖的比例更高,这对男女都是如此。超重和肥胖儿童的血糖、胰岛素和血脂水平显著高于消瘦儿童(所有指标均 P<0.0001)。儿童的所有肥胖指标均与心血管危险因素显著相关。

结论

沙特儿童总体肥胖和腹部肥胖的严重程度与心血管危险因素的更高患病率相关,其相关性强度因性别而异。

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