Clinical trial in a dish; A rewarding step towards translation & perspectives on its limitations.
出版信息
J Stem Cells Regen Med. 2019 Dec 24;15(2):16-17. doi: 10.46582/jsrm.1502005. eCollection 2019.
Abstract
摘要
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本文引用的文献
1
Increased mesodermal and mesendodermal populations by BMP4 treatment facilitates human iPSC line differentiation into a cardiac lineage.通过BMP4处理增加中胚层和中内胚层群体有助于将人类诱导多能干细胞系分化为心脏谱系。
J Stem Cells Regen Med. 2019 Dec 24;15(2):45-51. doi: 10.46582/jsrm.1502009. eCollection 2019.
2
Challenges in designing and executing clinical trials in a dish studies.在培养皿研究中设计和开展临床试验所面临的挑战。
J Pharmacol Toxicol Methods. 2018 Nov-Dec;94(Pt 2):73-82. doi: 10.1016/j.vascn.2018.09.002. Epub 2018 Sep 26.
3
Clinical Trials in a Dish: A Perspective on the Coming Revolution in Drug Development.临床前药物研发：从药物开发的革命角度看
**解析**：原文为一篇医学相关的学术论文，因此译文也应该尽量贴近学术风格。Clinical Trials in a Dish 直译是“在培养皿中的临床试验”，但结合文章上下文，可以理解为“临床前药物研发”，即新药在进入临床试验之前的研究阶段。因此将标题译为“临床前药物研发：从药物开发的革命角度看”。
SLAS Discov. 2018 Sep;23(8):765-776. doi: 10.1177/2472555218775028. Epub 2018 Jun 4.
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