Vitale Valentina, Viu Judit, Armengou Lara, Ríos José, Jose-Cunilleras Eduard
Am J Vet Res. 2020 Feb;81(2):147-152. doi: 10.2460/ajvr.81.2.147.
To evaluate the prognostic value of measuring heart rate variability (HRV) in horses with colic at the time of admission to a referral hospital.
51 horses > 1 year of age with colic (41 that survived [survivors] and 10 that died or were euthanized [nonsurvivors]).
HRV was recorded within 1 hour after admission by use of heart rate sensors with horses restrained in stocks. A 5-minute recording period was analyzed to obtain HRV measurements (eg, SD of R-R intervals [SDRR], root mean square of successive differences between R-R intervals [RMSSD], and geometric SDs determined from Poincaré plots [SD1 and SD2]). Variables associated with outcome (survival vs nonsurvival) were identified. Measurements were compared among diagnostic categories for colic (obstructive, inflammatory, or ischemic).
SDRR and RMSSD were significantly higher in survivors (median [25th to 75th percentile], 91.0 milliseconds [78.9 to 114.6 milliseconds] and 64.8 milliseconds [40.9 to 78.4 milliseconds], respectively) than in nonsurvivors (50.7 milliseconds [29.1 to 69.2 milliseconds] and 33.4 milliseconds [12.6 to 47.9 milliseconds], respectively). Similarly, SD1 and SD2 were significantly higher in survivors (48.3 milliseconds [28.9 to 60.9 milliseconds] and 111.3 milliseconds [93.0 to 146.6 milliseconds], respectively) than in nonsurvivors (23.7 milliseconds [8.9 to 33.9 milliseconds] and 65.1 milliseconds [33.7 to 91.9 milliseconds], respectively). The SDRR and SD2 were significantly higher for horses with obstructive colic than for horses with ischemic colic.
Analysis of HRV in horses with colic may provide information on the underlying cause and be helpful in identifying horses less likely to survive.
评估转诊医院收治的患急腹症马匹入院时测量心率变异性（HRV）的预后价值。
51匹1岁以上的患急腹症马匹（41匹存活[存活者]，10匹死亡或实施安乐死[非存活者]）。
入院后1小时内，使用心率传感器在马匹被固定于畜栏时记录HRV。分析5分钟的记录期以获得HRV测量值（例如，R-R间期标准差[SDRR]、R-R间期连续差值的均方根[RMSSD]以及根据庞加莱图确定的几何标准差[SD1和SD2]）。确定与结局（存活与非存活）相关的变量。对急腹症的诊断类别（阻塞性、炎症性或缺血性）之间的测量值进行比较。
存活者的SDRR和RMSSD显著高于非存活者（中位数[第25至75百分位数]，分别为91.0毫秒[78.9至114.6毫秒]和64.8毫秒[40.9至78.4毫秒]）（非存活者分别为50.7毫秒[29.1至69.2毫秒]和33.4毫秒[12.6至47.9毫秒]）。同样，存活者的SD1和SD2也显著高于非存活者（分别为48.3毫秒[28.9至60.9毫秒]和111.3毫秒[93.0至146.6毫秒]）（非存活者分别为23.7毫秒[8.9至33.9毫秒]和65.1毫秒[33.7至91.9毫秒]）。阻塞性急腹症马匹的SDRR和SD2显著高于缺血性急腹症马匹。
对患急腹症马匹的HRV分析可能提供有关潜在病因的信息，并有助于识别存活可能性较小的马匹。
