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用于改善脂质修饰的乳糖脑啡肽酶促糖基化的脂质体。

Liposomes for Improved Enzymatic Glycosylation of Lipid-Modified Lactose Enkephalin.

作者信息

Christie Michelle P, Simerska Pavla, Jen Freda E-C, Jennings Michael P, Toth Istvan

机构信息

School of Chemistry and Molecular Biosciences, The University of Queensland, Cooper Road, St Lucia, QLD 4072 (Australia), Fax: (+61) 7-33654273.

Institute for Glycomics, Griffith University, Parklands Drive, Southport, QLD 4125 (Australia).

出版信息

Chempluschem. 2013 Aug;78(8):793-796. doi: 10.1002/cplu.201300115. Epub 2013 Jun 21.

DOI:10.1002/cplu.201300115
PMID:31986686
Abstract

Liposomes and enzymes: Liposome formulations improved solubility of a lipid-modified lactose enkephalin and, when used in enzymatic transformation, led to a twofold increase in glycosylation in comparison to substrate solubilised in 5 % dimethyl sulfoxide (DMSO; see figure).

摘要

脂质体与酶

脂质体制剂提高了脂质修饰的乳糖脑啡肽的溶解度,并且在酶促转化中使用时,与溶解于5%二甲基亚砜(DMSO)中的底物相比,糖基化增加了两倍(见图)。

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