Christie Michelle P, Simerska Pavla, Jen Freda E-C, Jennings Michael P, Toth Istvan
School of Chemistry and Molecular Biosciences, The University of Queensland, Cooper Road, St Lucia, QLD 4072 (Australia), Fax: (+61) 7-33654273.
Institute for Glycomics, Griffith University, Parklands Drive, Southport, QLD 4125 (Australia).
Chempluschem. 2013 Aug;78(8):793-796. doi: 10.1002/cplu.201300115. Epub 2013 Jun 21.
Liposomes and enzymes: Liposome formulations improved solubility of a lipid-modified lactose enkephalin and, when used in enzymatic transformation, led to a twofold increase in glycosylation in comparison to substrate solubilised in 5 % dimethyl sulfoxide (DMSO; see figure).
脂质体制剂提高了脂质修饰的乳糖脑啡肽的溶解度,并且在酶促转化中使用时,与溶解于5%二甲基亚砜(DMSO)中的底物相比,糖基化增加了两倍(见图)。