Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, College of Medicine, University of South Alabama, Mobile.
Department of Comparative Medicine, Primate Research Laboratory, College of Medicine, University of South Alabama, Mobile.
Am J Primatol. 1984;6(2):103-113. doi: 10.1002/ajp.1350060204.
Serial measurements of estradiol (E2) and progesterone (P) were used to describe the ovarian cycle of the Bolivian squirrel monkey. Group-caged, sexually mature female squirrel monkeys, housed with males, were sampled daily between 0900 and 1100 hr. Sampling was carried out during the breeding and nonbreeding seasons, for periods of 19-20 days from September 1981 to May 1982. Seasonal differences in serum concentrations of E2 and P were found with low levels of E2 and P and an absence of preovulatory surges of E2 during the nonbreeding season. This pattern was also observed in some animals during the breeding season. An abrupt increase in serum P concentrations in December appeared to signal the onset of cycling. Cycling animals had well-defined peaks of E2 (450-9,500 pg/ml) followed by increasing levels of P, which were >200 ng/ml in some animals. After the breeding season, E2 and P levels returned to their initially low levels. Levels of both steroids in cycling animals were higher than those reported for other primates and for previous measurements made in squirrel monkeys. Cycle length based on time interval between consecutive E2 peaks varied from 6-12 days.
我们通过连续测量雌二醇（E2）和孕酮（P）来描述玻利维亚松鼠猴的卵巢周期。将性成熟的雌性松鼠猴与雄性松鼠猴一起关在群体笼中，每天在 0900 到 1100 小时之间进行采样。我们于 1981 年 9 月至 1982 年 5 月，在繁殖季节和非繁殖季节进行了为期 19-20 天的采样。我们发现，雌二醇和孕酮的血清浓度存在季节性差异，在非繁殖季节，E2 和 P 的水平较低，并且没有促排卵的 E2 激增。在一些动物中，这种模式在繁殖季节也存在。12 月血清 P 浓度的突然增加似乎标志着周期的开始。处于周期的动物具有明确的 E2 峰值（450-9500 pg/ml），随后 P 水平升高，一些动物的 P 水平>200ng/ml。繁殖季节结束后，E2 和 P 水平又恢复到最初的低水平。与其他灵长类动物和松鼠猴以前的测量值相比，处于周期的动物的两种类固醇水平更高。基于连续 E2 峰值之间的时间间隔的周期长度为 6-12 天。
