Institute of Special Animal and Plant Science, Chinese Academy of Agricultural Sciences, China; State Key Laboratory for Molecular Biology of Special Economic Animals, Changchun, China.
Institute of Special Animal and Plant Science, Chinese Academy of Agricultural Sciences, China; State Key Laboratory for Molecular Biology of Special Economic Animals, Changchun, China.
Anim Reprod Sci. 2020 Feb;213:106270. doi: 10.1016/j.anireprosci.2019.106270. Epub 2019 Dec 28.
This study was conducted to investigate the effects of dietary vitamin E (VE) supplementation on the reproductive performance of female mink, preweaning growth performance of their kits, and antioxidative status and immune functions of dams and kits. Yearling mink dams (n = 180) were randomly assigned to five treatment groups (n = 36). The dietary treatments included a basal diet supplemented with VE at 0 (control), 80, 160, 320, or 640 mg/kg DM. Compared with the control, the addition of 160-320 mg/kg VE decreased (P = 0.0362) the percentage of pre-weaning mortality of mink kits. At weaning, the average body weight was greater (P = 0.0408) in kits fed 320 mg/kg supplemental VE. In mink dams, the addition of 80-320 mg/kg VE increased (P = 0.0125) serum SOD. Supplementation of 320 or 640 mg/kg VE decreased (P = 0.0260) serum reactive oxygen species (ROS). Furthermore, feeding a large dose of VE (640 mg/kg diet) resulted in increased (P = 0.0245) serum α-tocopherol. In mink kits, the addition of 320 or 640 mg/kg VE increased serum α-tocopherol (P = 0.0207) and IgG (P = 0.0464). Supplementation of 640 mg/kg VE decreased (P = 0.0471) serum ROS. The present results indicate that VE supplementation improved the antioxidative status of mink dams and enhanced the immune functions, decreased pre-weaning mortality and enhanced weaning weight of their kits. Taken together, the effective VE supplementation was 320 mg/kg of diet for yearling female mink.
本研究旨在探讨日粮添加维生素 E（VE）对母貂繁殖性能、仔貂哺乳期生长性能、母貂和仔貂抗氧化状态及免疫功能的影响。选用 180 只育成期母貂，随机分为 5 个处理组（n=36），日粮中 VE 添加量分别为 0（对照组）、80、160、320 和 640mg/kg 饲粮干物质。与对照组相比，添加 160-320mg/kg VE 降低了仔貂哺乳期死亡率（P=0.0362）。断奶时，添加 320mg/kg VE 组仔貂的平均体重显著高于对照组（P=0.0408）。母貂血清中超氧化物歧化酶（SOD）活性在添加 80-320mg/kg VE 时显著升高（P=0.0125）。添加 320 和 640mg/kg VE 降低了血清活性氧（ROS）含量（P=0.0260）。此外，饲粮添加高剂量 VE（640mg/kg 饲粮）使血清α-生育酚含量增加（P=0.0245）。添加 320 和 640mg/kg VE 提高了仔貂血清α-生育酚（P=0.0207）和 IgG（P=0.0464）水平。添加 640mg/kg VE 降低了血清 ROS 含量（P=0.0471）。研究表明，VE 可改善母貂的抗氧化状态，增强仔貂的免疫功能，降低哺乳期仔貂死亡率，提高断奶仔貂体重。综合来看，育成期母貂的有效 VE 添加量为 320mg/kg 饲粮。
