Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.
Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia; Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.
Toxicon. 2020 Jan 30;174:26-31. doi: 10.1016/j.toxicon.2019.12.158. Epub 2019 Dec 24.
Brachiaria decumbens (signal grass) is a highly productive tropical grass that is widespread in some tropical countries due to its adaptation to a wide range of environments and soil types. However, a limiting factor for the use of this grass is its toxicity from steroidal saponins. Sporadic outbreaks of hepatogenous photosensitization in ruminants grazing on this grass have been reported. Sheep are more susceptible than other animal species and the young are more susceptible than adults. This review article will critically shed light on the B. decumbens profile, its toxic compounds, mechanisms, clinical responses, blood profile alterations, pathological changes, and acute phase responses related to signal grass intoxication. Further research is needed to integrate new findings on B. decumbens intoxication with previous preventive and therapeutic trials to minimize or remove its deleterious toxic effect.
弯叶画眉草（signal grass）是一种高产的热带禾草，由于其对广泛的环境和土壤类型的适应性，在一些热带国家广泛分布。然而，这种草的一个限制因素是其甾体皂甙的毒性。有报道称，放牧这种草的反刍动物会间歇性地发生肝原性光敏性。绵羊比其他动物物种更容易受到影响，幼畜比成年动物更容易受到影响。本文综述将批判性地阐述弯叶画眉草的特性、其有毒化合物、作用机制、临床反应、血液参数改变、病理变化以及与 signal grass 中毒相关的急性期反应。需要进一步的研究来整合弯叶画眉草中毒的新发现与以前的预防和治疗试验，以最小化或消除其有害的毒性作用。
