Hospital Universitario de Fuenlabrada , Madrid, Spain.
Facultad de Medicina, Universidad Rey Juan Carlos , Móstoles, Madrid, Spain.
Postgrad Med. 2020 Apr;132(3):296-300. doi: 10.1080/00325481.2020.1718388. Epub 2020 Jan 28.
Studies in recent years suggest an increase in the incidence of sepsis but a decrease in mortality. The aim of this study is to describe the characteristics of patients discharged after a sepsis episode from Spanish internal medicine services between 2005 and 2015.
Since 2005, in which there were a total of 4,319 cases, sepsis hospitalizations has been consistently increasing yearly reaching a total of 25,820 cases in 2015. We observed that septic patients are older and with higher comorbidity than the general population admitted in Internal Medicine. On the other hand, we found a decreasing trend in the mortality rates of patients with sepsis in our series going from 35.7% in 2005 to 30.1% in 2015 (p < 0.005).
In our study, a higher comorbidity at admission and developing complications during admittance, conditioned a higher probability of death due to sepsis. The variables that were associated with increased mortality risk were age, acute renal failure, acute respiratory failure, lactic acidosis, septic shock and chronic heart failure.
As in other similar studies, we observed an increase in the hospitalizations by sepsis as a diagnosis at discharge during the study period in Internal Medicine services with a simultaneous decrease in mortality. Comorbidity at admission and complications during admittance condition mortality.
近年来的研究表明，脓毒症的发病率有所增加，但死亡率有所下降。本研究旨在描述 2005 年至 2015 年期间，从西班牙内科住院服务出院的脓毒症患者的特征。
自 2005 年以来，每年的脓毒症住院人数持续增加，总计达到 2015 年的 25820 例。我们观察到，脓毒症患者比内科普通人群年龄更大，合并症更多。另一方面，我们发现本研究中脓毒症患者的死亡率呈下降趋势，从 2005 年的 35.7%下降到 2015 年的 30.1%（p<0.005）。
在我们的研究中，入院时合并症更多，入院期间发生并发症，都会增加因脓毒症死亡的可能性。与死亡风险增加相关的变量是年龄、急性肾衰竭、急性呼吸衰竭、乳酸酸中毒、脓毒性休克和慢性心力衰竭。
与其他类似研究一样，我们观察到内科住院服务中，作为出院诊断的脓毒症住院人数在研究期间增加，同时死亡率下降。入院时的合并症和入院期间的并发症影响死亡率。
