Corneal Unit, Sydney Eye Hospital, Sydney, Australia.
Discipline of Ophthalmology, Sydney Medical School, The University of Sydney, Sydney, Australia; and.
Cornea. 2020 Aug;39(8):1048-1051. doi: 10.1097/ICO.0000000000002270.
To report the 5-year outcomes of the first reported case of bilateral Descemet stripping only (DSO) for Fuchs endothelial corneal dystrophy (FECD) at our center. Visual, biomicroscopic, and confocal microscopic findings are described.
A retrospective case report.
A 55-year-old woman with bilateral FECD was referred with decreased visual acuity and blurred vision that interrupted activities of daily living. She underwent sequential 4-mm DSO procedures 6 months apart, with early postoperative results previously reported. Subjective visual symptoms, visual acuity, and corneal edema were analyzed at 1 month, 3 months, 6 months, 12 months, 2 years, 3 years, and 5 years postoperatively. Best corrected visual acuity of 0.0 (logarithm of the minimum angle of resolution) and corneal clearance were achieved in the third month after the procedure. These results have remained stable in the 5-year follow-up period.
Early postoperative results from DSO surgery are encouraging, but questions remain regarding its longevity. Publication of longer-term outcomes such as this is necessary to establish the validity of this procedure as an intervention for FECD.
报告首例在我中心行双侧仅撕除后弹力层（Descemet stripping only，DSO）治疗 Fuchs 内皮角膜营养不良（FECD）的 5 年结果。描述了视力、眼前节和共聚焦显微镜的发现。
回顾性病例报告。
一名 55 岁女性因双侧 FECD 就诊，视力下降和视物模糊影响日常生活。她接受了 6 个月间隔的 4-mm DSO 序贯手术，此前已报道了早期术后结果。术后 1 个月、3 个月、6 个月、12 个月、2 年、3 年和 5 年分别分析了主观视觉症状、视力和角膜水肿情况。术后第 3 个月即达到最佳矫正视力 0.0（最小分辨角对数）和角膜清亮。在 5 年的随访期间，这些结果保持稳定。
DSO 手术后的早期结果令人鼓舞，但该手术的长期效果仍存在疑问。需要发表更长时间的结果，例如本研究，以确立该手术作为 FECD 干预措施的有效性。
