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眶部血管平滑肌瘤 1 例罕见报告。

A rare case of orbital angioleiomyoma.

机构信息

Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust , Manchester, UK.

出版信息

Orbit. 2021 Feb;40(1):60-64. doi: 10.1080/01676830.2020.1717547. Epub 2020 Jan 29.

DOI:10.1080/01676830.2020.1717547
PMID:31994422
Abstract

A 65-year old woman presented with 3-year history of painless, gradual swelling of the right upper eyelid associated with proptosis. Computed tomography (CT) and magnetic resonance imaging (MRI) of the orbit showed a well circumscribed soft tissue mass in the supero-lateral orbit. An excision biopsy of the lesion was performed via lateral orbitotomy. Histopathology examination and immunochemistry staining confirmed the diagnosis of cavernous angioleiomyoma. The tumour was excised completely. Orbital angioleiomyoma is a rare benign tumour and the lesion can cause visual morbidity, particularly when intraconal. Despite sophisticated imaging modalities, histopathological analysis is essential for diagnosis. Angioleiomyoma should be included in the differential diagnosis of well-defined orbital lesions. Complete surgical excision carries a low risk of recurrence.

摘要

一位 65 岁女性,3 年前出现右上眼睑无痛性、进行性肿胀,伴有眼球突出。眼眶的计算机断层扫描(CT)和磁共振成像(MRI)显示在眼眶的外上象限有一个边界清楚的软组织肿块。通过外侧眼眶切开术对病变进行了切除活检。组织病理学检查和免疫化学染色证实了海绵状血管平滑肌脂肪瘤的诊断。肿瘤被完全切除。眼眶血管平滑肌脂肪瘤是一种罕见的良性肿瘤,当病变位于眶内时可导致视力损害,特别是当病变位于眶内时。尽管有复杂的成像方式,但组织病理学分析对于诊断至关重要。血管平滑肌脂肪瘤应纳入边界清楚的眼眶病变的鉴别诊断。完全手术切除复发风险低。

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引用本文的文献

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Intracranial angioleiomyoma mimicking meningioma: an uncommon tumor with favorable outcome and frequent GJA4 mutation.颅内血管平滑肌脂肪瘤酷似脑膜瘤:一种少见的肿瘤,具有良好的预后和频繁的 GJA4 突变。
Neurosurg Rev. 2024 Nov 11;47(1):842. doi: 10.1007/s10143-024-03079-4.
2
The underestimated incidence of an orbital angioleiomyoma is possibly associated with an orbital cavernous hemangioma: illustrative case.眼眶血管平滑肌瘤被低估的发病率可能与眼眶海绵状血管瘤有关:病例报告
J Neurosurg Case Lessons. 2021 May 24;1(21):CASE2172. doi: 10.3171/CASE2172.