Ozer Songul Peltek, Barut Saime Gul, Ozer Bahri, Catal Oguz, Sit Mustafa
. Abant İzzet Baysal University Hospital, Department of Pathology, Bolu, Turkey.
. Haseki Training and Research Hospital, Department of Pathology, İstanbul, Turkey.
Rev Assoc Med Bras (1992). 2019 Dec;65(12):1442-1447. doi: 10.1590/1806-9282.65.12.1442.
Tumor budding is a parameter that is increasingly understood in colorectal carcinomas. We aimed to investigate the relationship between tumor budding, prognostic factors, and survival.
A total of 185 patients who had undergone colorectal surgery were observed. Tumor budding, the tumor budding score, and the relationship between these and prognostic factors, and survival investigated.
Tumor budding was found in 91 (49.2%) cases. The relationship between the tumor budding score and histological grade, lymphovascular invasion, perineural invasion, pathological lymph node stage, and mortality rates were significant.
In our study, the relationship between tumor budding and survival is very strong. Considering these findings and the literature, the prognostic significance of tumor budding becomes clear and should be stated in pathology reports.
肿瘤芽生是结直肠癌中一个越来越被人们所了解的参数。我们旨在研究肿瘤芽生、预后因素和生存率之间的关系。
观察了总共185例接受结直肠手术的患者。研究了肿瘤芽生、肿瘤芽生评分以及它们与预后因素和生存率之间的关系。
在91例（49.2%）病例中发现了肿瘤芽生。肿瘤芽生评分与组织学分级、淋巴管侵犯、神经周围侵犯、病理淋巴结分期和死亡率之间的关系具有显著性。
在我们的研究中，肿瘤芽生与生存率之间的关系非常密切。考虑到这些发现和文献，肿瘤芽生的预后意义变得清晰，应在病理报告中说明。
