Department of Psychiatry, College of Health Sciences, Makerere University, Mulago, Uganda.
NURTURE Mental Health subgroup, College of Health Sciences, Makerere University, Mulago, Uganda.
PLoS One. 2020 Jan 29;15(1):e0218843. doi: 10.1371/journal.pone.0218843. eCollection 2020.
Hospital based studies for psychotic disorders are scarce in low and middle income countries. This may impact on development of intervention programs.
We aimed to determine the burden of psychotic disorders among first treatment contact patients at the national psychiatric referral hospital in Uganda.
A retrospective patient chart-file review was carried out in March 2019 for all patients presenting to the hospital for the first time in the previous year. Patients were categorised into those with and without psychotic disorders. We collected sociodemographic data on age, gender, occupation, level of education, ethnicity, religion and home district. We determined the one year prevalence of psychotic disorders among first treatment contact patients. Using logistic regression models, we also determined the association between psychotic disorders and various exposure variables among first treatment contact patients.
In 2018, 63% (95% CI: 60.2-65.1) of all first time contact patients had a psychosis related diagnosis. Among the patients with psychotic disorders, the median age was 29 years (IQR 24-36). Most of the patients were male (62.8%) and unemployed (63.1%). After adjusting for patients' residence, psychotic disorders were found to be more prevalent among the female gender [OR 1.58 (CI1.46-1.72)] and those of Pentecostal faith [OR 1.25 (CI 1.10-1.42)].
Among first treatment contact patients in Uganda, there is a large burden of psychotic disorders. The burden was more prevalent among females as well as people of Pentecostal faith who seemed to use their church for faith-based healing. Incidence studies are warranted to determine if this phenomenon is replicated at illness onset.
在中低收入国家,基于医院的精神病学研究较为匮乏。这可能会影响干预项目的开展。
我们旨在确定乌干达国家精神病学转诊医院首次就诊患者的精神病性障碍负担。
2019 年 3 月,我们对过去一年内在该院首次就诊的所有患者的病历进行了回顾性患者图表文件审查。患者分为有和无精神病性障碍两类。我们收集了年龄、性别、职业、教育程度、族裔、宗教和家乡地区等社会人口学数据。我们确定了首次就诊患者中精神病性障碍的一年患病率。使用逻辑回归模型,我们还确定了首次就诊患者中精神病性障碍与各种暴露变量之间的关联。
2018 年,所有首次就诊患者中,有 63%(95%CI:60.2-65.1)有精神障碍相关诊断。在有精神病性障碍的患者中,中位年龄为 29 岁(IQR 24-36)。大多数患者为男性(62.8%)和无业(63.1%)。在调整了患者居住地后,发现女性中精神病性障碍更为常见[OR 1.58(CI1.46-1.72)],以及五旬节信仰者[OR 1.25(CI 1.10-1.42)]。
在乌干达首次就诊的患者中,精神病性障碍的负担很大。这种负担在女性和五旬节信仰者中更为常见,他们似乎利用教堂进行基于信仰的治疗。有必要进行发病研究,以确定这种现象是否在发病时重现。