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冠心病患者冠状动脉支架置入术后的D型人格:一项前瞻性研究

[Type D personality in patients with coronary heart disease underwent coronary stenting: a prospective study].

作者信息

Pushkarev G S, Kuznetsov V A, Fisher Ya A

机构信息

Tomsk National Research Medical Center, Russian Academy of Sciences, Tyumen Cardiology Research Center.

出版信息

Kardiologiia. 2019 Nov 1;59(12S):18-24. doi: 10.18087/cardio.n342.

DOI:10.18087/cardio.n342
PMID:31995722
Abstract

To evaluate the type D personality relation with clinical and instrumental parameters in patients with coronary heart disease (CHD) underwent coronary stenting (CS) and to determine the influence of the personality type D on the prognosis in these patients within one year after CS. Material and methods. Into prospective study we included 977 patients (740 men and 237 women) aged 33 to 86 years (mean age 58.7±9.4) who underwent CS. The Cox proportional hazard regression model was used to estimate the relative risk (RR) with a 95% confidence interval (CI) of the end point. The end points included death from all causes, death from cardiovas- cular disease (CVD), myocardial infarction (fatal + non-fatal) (MI), non-fatal myocardial infarction (non-fatal MI), unstable angina (UA), and stroke. Results. Type D personality was found in 31.8% patients. These did not differ from the others in terms of age, gender, main cardiovascular risk factors. Patients of D-type had tendency to the increase of diabetes diagnosed - 25.1% vs 20.3% (p=0.09). At the same time D-type patients had more prevalent ≥2 myocardial infarction in anamnesis - 9.0% vs 4.5% (p=0,006) among those with post infarction cardiosclerosis. There was no difference between the groups according to echocardiography and the short-term outcomes of CS. During the prospective study period (12±1.8 months) 24 patients (2.4%) died from all causes, 21 patients (2.1%) died from CVD. MI developed in 47 patients (4.8%) of whom, 23 patients (2.4%) underwent non-fatal MI. In 50 patients (5.1%) ischemic heart disease in a prospective period complicated UA. In 8 patients (0.8%) developed a stroke. There was no effect of personality type D on the prognosis in patients with CHD who underwent CS for 1 year after surgery. Conclusion. Among CHD patients underwent CS, type D personality was found in 31.8%. There is no link for type D personality and severity of CHD clinically as well as the short-term and long-term outcomes of CS.

摘要

评估冠心病(CHD)患者接受冠状动脉支架置入术(CS)后D型人格与临床及器械参数的关系,并确定D型人格对这些患者CS术后一年内预后的影响。材料与方法。前瞻性研究纳入了977例接受CS的患者(740例男性和237例女性),年龄33至86岁(平均年龄58.7±9.4岁)。采用Cox比例风险回归模型估计终点事件的相对风险(RR)及95%置信区间(CI)。终点事件包括各种原因导致的死亡、心血管疾病(CVD)死亡、心肌梗死(致死性+非致死性)(MI)、非致死性心肌梗死(非致死性MI)、不稳定型心绞痛(UA)和中风。结果。31.8%的患者为D型人格。这些患者在年龄、性别、主要心血管危险因素方面与其他患者无差异。D型患者糖尿病诊断率有上升趋势——25.1%对20.3%(p = 0.09)。同时,D型患者既往有≥2次心肌梗死的情况在梗死后心肌硬化患者中更普遍——9.0%对4.5%(p = 0.006)。两组在超声心动图及CS短期结局方面无差异。在前瞻性研究期间(12±1.8个月),24例患者(2.4%)因各种原因死亡,21例患者(2.1%)死于CVD。47例患者(4.8%)发生MI,其中23例患者(2.4%)发生非致死性MI。50例患者(5.1%)在随访期缺血性心脏病并发UA。8例患者(0.8%)发生中风。D型人格对接受CS的CHD患者术后1年的预后无影响。结论。在接受CS的CHD患者中,31.8%为D型人格。D型人格与CHD的临床严重程度以及CS的短期和长期结局均无关联。

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