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过去十年中国黄土高原典型地方性氟中毒地区儿童氟暴露的健康风险。

Health risk in children to fluoride exposure in a typical endemic fluorosis area on Loess Plateau, north China, in the last decade.

机构信息

School of Life Science, Shanxi University, Taiyuan, Shanxi, 030006, China; Taiyuan Monitoring Station of National Urban Water Quality Monitoring Network, Taiyuan, Shanxi, 030009, China.

School of Physical Education, Shanxi University, Taiyuan, Shanxi, 030006, China.

出版信息

Chemosphere. 2020 Mar;243:125451. doi: 10.1016/j.chemosphere.2019.125451. Epub 2019 Nov 23.

Abstract

Excessive and inadequate intake of fluoride may cause adverse effects in children, such as dental caries and dental fluorosis. This study reports the results of monitoring fluoride concentrations in drinking water from an endemic fluorosis region during the ten-year period (2008 through 2017). The fluoride concentration had a range of 0.03-9.42 mg L (mean = 0.55 ± 0.01 mg L). Approximately 10%, 1.3% and 0.06% children are at risk for dental decay, dental fluorosis and skeletal fluorosis, respectively. Probabilistic risks for children were assessed and the fluoride endemic areas were marked by GIS mapping system. On several water consumption points, the hazard quotient (HQ) values for children were higher than 1, indicating potential non-cancer health risks due to fluoride exposure. The results of this study will help governmental agencies to develop better policies for protecting children from exposure to fluoride.

摘要

过量和不足的氟摄入可能会对儿童造成不良影响,如龋齿和氟斑牙。本研究报告了在十年期间(2008 年至 2017 年)对地方性氟中毒地区饮用水中氟浓度监测的结果。氟浓度范围为 0.03-9.42mg/L(平均值=0.55±0.01mg/L)。分别约有 10%、1.3%和 0.06%的儿童分别面临龋齿、氟斑牙和氟骨症的风险。利用 GIS 制图系统对儿童的概率风险进行了评估,并对地方性氟中毒地区进行了标记。在几个饮水点,儿童的危害商数(HQ)值高于 1,表明由于氟暴露可能存在非癌症健康风险。本研究的结果将有助于政府机构制定更好的政策,以保护儿童免受氟暴露。

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