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一名怀有单绒毛膜双羊膜囊双胎的22岁女性发生快速进展的HELLP综合征及大面积肝破坏。

Rapidly progressing HELLP syndrome and massive liver destruction in a 22-year-old female pregnant with monochorionic diamniotic gemelli.

作者信息

Brøsen Julie, Stærk Dorte, Feldthusen Anne-Dorthe, Rasmussen Allan, Damholt Mette Brimnes

机构信息

Nephrology, Rigshospitalet, Copenhagen, Denmark.

Radiology, Rigshospitalet, Copenhagen, Denmark.

出版信息

BMJ Case Rep. 2020 Jan 28;13(1):e229458. doi: 10.1136/bcr-2019-229458.

Abstract

Haemolysis Elevated Liver parameters and Low Platelets (HELLP) syndrome can present with abdominal pain as the only symptom. It can be rapid with failure of multiple organs and is a cause of maternal death. A 22-year-old female pregnant with twins contacted her local hospital due to abdominal pain. Within 20 hours of the debut of the abdominal pain, a caesarean section was performed, the patient was re-operated due to the suspicion of abdominal bleeding. Bescause she was hypotensive and blood tests showed signs of liver destruction and acidosis, she was transferred to the intensive care unit (ICU). During an admission of 40 days, the patient received 5 plasmapheresis treatments and 10 courses of haemodialysis. CT scans showed massive liver haematomas intraparenchymal and subcapsular. The CT scan images are very interesting and included in the case report.This case presents a good prognosis after a rapid progression of HELLP in spite of a dramatic clinical presentation. This topic is of great interest to a wide spectre of clinicians, as an early multidisciplinary approach is necessary.

摘要

溶血、肝酶升高和血小板减少(HELLP)综合征可能仅以腹痛为唯一症状出现。它可能发展迅速,导致多器官功能衰竭,是孕产妇死亡的一个原因。一名怀有双胞胎的22岁女性因腹痛联系了当地医院。在腹痛出现后的20小时内,进行了剖宫产手术,由于怀疑腹腔出血,患者再次接受手术。由于她血压过低,血液检查显示有肝损伤和酸中毒迹象,她被转入重症监护病房(ICU)。在住院的40天里,患者接受了5次血浆置换治疗和10次血液透析疗程。CT扫描显示肝实质内和包膜下有大量肝血肿。CT扫描图像非常有趣,已纳入病例报告。尽管临床表现严重,但该病例在HELLP快速进展后仍呈现出良好的预后。由于需要早期采取多学科方法,这个话题受到了广泛临床医生的极大关注。

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本文引用的文献

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