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终末期梅尼埃病患者人工耳蜗植入术后的长期眩晕控制:一项基于问卷的回顾性横断面研究。

Long-term vertigo control after cochlear implantation in patients with end-stage Menière's disease : A retrospective questionnaire-based cross-sectional study.

作者信息

Kurz Annabella, Auinger Alice, Arnoldner Christoph

机构信息

Department of Otolaryngology, Head and Neck Surgery, Medical University of Vienna - AKH Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

出版信息

Wien Klin Wochenschr. 2020 Sep;132(17-18):521-525. doi: 10.1007/s00508-019-01605-9. Epub 2020 Jan 29.

Abstract

BACKGROUND

Menière's disease (MD) is a symptom complex which is characterized by episodes of vertigo, tinnitus and fluctuating sensorineural hearing loss, which worsens during the course of the disease.

OBJECTIVE

Vertigo attacks (MD functional level scale) before compared to after cochlear implantation in patients with end-stage MD.

DESIGN AND PATIENTS

In this questionnaire-based cross-sectional study eight patients with end-stage MD, who received a cochlear implant (CI) were analyzed.

MAIN OUTCOME MEASURE

The effect of the CI on vertigo was measured preoperatively and postoperatively with the Menière's disease functional level scale and the Menière's disease outcome questionnaire. The primary outcome parameter influence of vertigo attacks on daily living was analyzed using the non-parametric Wilcoxon signed rank test before and after CI.

SETTING

Department of otolaryngology of a medical university.

RESULTS

The primary outcome measure influence of vertigo attacks on daily living as measured by the MD functional level scale improved significantly after CI.

CONCLUSION

A CI can be an adequate treatment for vertigo attacks in patients with end-stage MD; however, due to the small sample size additional (multicenter) trials are necessary to confirm the findings.

摘要

背景

梅尼埃病(MD)是一种症状复合体,其特征为眩晕发作、耳鸣以及波动性感音神经性听力损失,且在疾病过程中会恶化。

目的

比较终末期梅尼埃病患者人工耳蜗植入前后的眩晕发作情况(MD功能水平量表)。

设计与患者

在这项基于问卷的横断面研究中,分析了8例接受人工耳蜗植入(CI)的终末期梅尼埃病患者。

主要观察指标

术前和术后使用梅尼埃病功能水平量表和梅尼埃病结局问卷测量人工耳蜗植入对眩晕的影响。使用非参数Wilcoxon符号秩检验分析人工耳蜗植入前后眩晕发作对日常生活的主要结局参数影响。

地点

一所医科大学的耳鼻喉科。

结果

通过MD功能水平量表测量,人工耳蜗植入后眩晕发作对日常生活的主要观察指标影响显著改善。

结论

人工耳蜗植入可作为终末期梅尼埃病患者眩晕发作的一种有效治疗方法;然而,由于样本量小,需要进行额外的(多中心)试验来证实这些发现。

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本文引用的文献

1
International consensus (ICON) on treatment of Ménière's disease.梅尼埃病治疗的国际共识(ICON)
Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Feb;135(1S):S29-S32. doi: 10.1016/j.anorl.2017.12.006. Epub 2018 Jan 12.
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Cochlear Implantation in Ménière's Disease.
JAMA Otolaryngol Head Neck Surg. 2014 Jun;140(6):535-9. doi: 10.1001/jamaoto.2014.550.
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Cochlear implantation in Ménière's disease patients.梅尼埃病患者的人工耳蜗植入
Otol Neurotol. 2014 Mar;35(3):421-5. doi: 10.1097/MAO.0000000000000247.
8
Delayed cochlear implantation after surgical labyrinthectomy.手术性迷路切除术后的延迟人工耳蜗植入
J Laryngol Otol. 2012 Jan;126(1):63-5. doi: 10.1017/S0022215111002374. Epub 2011 Sep 14.

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