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韩国卫生专业人员对精准医学的看法:一项混合方法研究。

Views on Precision Medicine among Health Professionals in Korea: A Mixed Methods Study.

机构信息

Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea.

Department of Digital Health, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Yonsei Med J. 2020 Feb;61(2):192-197. doi: 10.3349/ymj.2020.61.2.192.

DOI:10.3349/ymj.2020.61.2.192
PMID:31997629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6992457/
Abstract

This study aimed to investigate awareness, attitudes, and perspectives on precision medicine among health professionals in Korea and to identify issues that need to be addressed before implementing precision medicine. Mixed methods research was applied. For qualitative research, a semi-structured focus group interview was conducted with six health professionals. For quantitative research, a self-reported survey was administered. A total of 542 health professionals participated in the survey, and 526 completed the entire questionnaire. Health professionals showed positive attitudes toward precision medicine. About 95-96% of respondents agreed that precision medicine will be effective in treatment and precise diagnosis, and 69.9% reported that they would participate as study subjects. Meanwhile, they expressed concerns regarding educating patients and health professionals in precision medicine and developing research and data sharing infrastructure. Also, they emphasized the importance of developing precision medicine in an equitable way. Despite varying levels of awareness of precision medicine, the health professionals expressed a willingness to engage in precision medicine research, and recommended that health professionals work closely with policymakers to design precision medicine in a way that can be effectively adopted. Health professionals showed had a positive, but cautious, attitude toward precision medicine. The results of this study suggest areas to be addressed before ushering in precision medicine in Korea.

摘要

本研究旨在调查韩国卫生专业人员对精准医学的认识、态度和观点,并确定在实施精准医学之前需要解决的问题。采用混合方法研究。定性研究采用半结构式焦点小组访谈,对 6 名卫生专业人员进行访谈。定量研究采用自我报告式问卷调查。共有 542 名卫生专业人员参与了调查,其中 526 人完成了整个问卷。卫生专业人员对精准医学持积极态度。约 95-96%的受访者同意精准医学将在治疗和精确诊断方面有效,69.9%的受访者表示他们将作为研究对象参与。同时,他们对精准医学患者和卫生专业人员教育以及研发和数据共享基础设施的发展表示担忧。此外,他们强调以公平的方式开发精准医学的重要性。尽管卫生专业人员对精准医学的认识程度不同,但他们表示愿意参与精准医学研究,并建议卫生专业人员与政策制定者密切合作,以能够有效采用的方式设计精准医学。卫生专业人员对精准医学持积极但谨慎的态度。本研究结果提示在韩国引入精准医学之前需要解决的问题。

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本文引用的文献

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2
Genomic medicine 2025: France in the race for precision medicine.2025年的基因组医学:法国参与精准医学竞赛。
Lancet. 2016 Dec 10;388(10062):2872. doi: 10.1016/S0140-6736(16)32467-9.
3
From "Personalized" to "Precision" Medicine: The Ethical and Social Implications of Rhetorical Reform in Genomic Medicine.从“个性化”到“精准”医学:基因组医学中修辞改革的伦理和社会影响。
Hastings Cent Rep. 2016 Sep;46(5):21-33. doi: 10.1002/hast.614.
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BMC Med Genomics. 2016 May 10;9(1):23. doi: 10.1186/s12920-016-0183-8.
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China embraces precision medicine on a massive scale.中国正在大规模推行精准医学。
Nature. 2016 Jan 7;529(7584):9-10. doi: 10.1038/529009a.
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Perceptions of Personalized Medicine in an Academic Health System: Educational Findings.学术健康系统中个性化医疗的认知:教育成果
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Precision medicine--personalized, problematic, and promising.精准医学——个性化、存在问题且充满希望。
N Engl J Med. 2015 Jun 4;372(23):2229-34. doi: 10.1056/NEJMsb1503104. Epub 2015 May 27.
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The precision medicine initiative: a new national effort.精准医学计划:一项新的全国性行动。
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