Malekpour Alamdari Nasser, Bayat Fariba, Bakhtiyari Mahmood, Noori Mehran
Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.
J Tehran Heart Cent. 2019 Jul;14(3):128-133.
Bariatric surgery is efficiently associated with the long-term resolution of obesity and its related morbidities. Not only can this surgical modality improve the metabolic profile, diastolic and systolic cardiac functions, and the clinical symptoms of heart failure or cardiomyopathy, but it can also reduce the atherosclerosis risk, ventricular mass, and pericardial fat thickness. The aim of the present study was to evaluate the effects of weight loss on echocardiographic parameters 1 year after sleeve gastrectomy. This quasi-experimental study, conducted in Modarres Hospital, Tehran, Iran, from September 2016 to September 2017, recruited 101 patients. Those with morbid obesity (body mass index ≥40 kg/m) had undergone surgery 1 year before the study commencement. All the patients underwent sleeve gastrectomy. The data of echocardiographic indices before and 1 year after surgery were recorded and analyzed. The mean age of the participants was 37.11±9.81 years. The majority of the study participants were female (n=77, 76.2%). During the first postoperative year, the mean weight loss was 43.82±14.53 kg. The mean systolic blood pressure was 137.96±19.60 mmHg and 123.37±9.60 mmHg before sleeve gastrectomy and 1 year afterward, respectively (P<0.001). The mean left ventricular size was 48.22±4.04 mm and 44.97±5.70 mm before sleeve gastrectomy and 1 year postoperatively, correspondingly (P<0.001). The mean pulmonary artery pressure was 28.88±5.25 mmHg and 24.10±4.78 mmHg before sleeve gastrectomy and 1 year after surgery, respectively (P<0.001). The mean left atrial size was 35.72±3.32 mm and 33.12±3.52 mm before sleeve gastrectomy and 1 year thereafter, correspondingly (P<0.001). Weight loss resulting from sleeve gastrectomy may improve systolic blood pressure, left atrial and left ventricular size, and pulmonary artery pressure.
减重手术与肥胖及其相关疾病的长期缓解有效相关。这种手术方式不仅可以改善代谢状况、舒张期和收缩期心脏功能以及心力衰竭或心肌病的临床症状，还可以降低动脉粥样硬化风险、心室质量和心包脂肪厚度。本研究的目的是评估袖状胃切除术后1年体重减轻对超声心动图参数的影响。这项准实验研究于2016年9月至2017年9月在伊朗德黑兰的莫达雷斯医院进行，招募了101名患者。那些患有病态肥胖（体重指数≥40kg/m²）的患者在研究开始前1年接受了手术。所有患者均接受了袖状胃切除术。记录并分析了手术前和手术后1年的超声心动图指标数据。参与者的平均年龄为37.11±9.81岁。大多数研究参与者为女性（n = 77，76.2%）。在术后的第一年，平均体重减轻了43.82±14.53kg。袖状胃切除术前和术后1年的平均收缩压分别为137.96±19.60mmHg和123.37±9.60mmHg（P<0.001）。袖状胃切除术前和术后1年的平均左心室大小分别为48.22±4.04mm和44.97±5.70mm（P<0.001）。袖状胃切除术前和术后1年的平均肺动脉压分别为28.88±5.25mmHg和24.10±4.78mmHg（P<0.001）。袖状胃切除术后的体重减轻可能会改善收缩压、左心房和左心室大小以及肺动脉压。
