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血管性血友病因子裂解蛋白酶前体/ADAMTS13 比值是肝移植后血栓性微血管病的有用标志物：一例儿科病例报告。

vWFpp/ADAMTS13 ratio is a useful marker of postliver transplantation thrombotic microangiopathy: A pediatric case report.

作者信息

Duquenne Lisa, Balbeur Samuel, Everard Emilie, Reding Raymond, Eeckhoudt Stéphane, Brichard Bénédicte, Godefroid Nathalie, Derycke Emilien, Komuta Mina, Scheers Isabelle, Smets Françoise, Sokal Etienne, Stéphenne Xavier

机构信息

Division of Paediatric Gastroenterology and Hepatology Department of Paediatrics Cliniques Universitaires Saint Luc Université Catholique de Louvain Brussels Belgium.

Division of Paediatric Surgery Department of Surgery Cliniques Universitaires Saint Luc Université Catholique de Louvain Brussels Belgium.

出版信息

Clin Case Rep. 2019 Dec 10;8(1):41-46. doi: 10.1002/ccr3.2495. eCollection 2020 Jan.

DOI:10.1002/ccr3.2495
PMID:31998483
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6982510/
Abstract

vWFpp/ADAMTS13 ratio should be further studied as a useful marker for diagnosis of thrombotic microangiopathy postliver transplantation. Immunosuppressive regimen modification and plasma supplementation can lead to recovery.

摘要

血管性血友病因子裂解蛋白酶原/ADAMTS13 比值作为肝移植后血栓性微血管病诊断的有用标志物应进一步研究。调整免疫抑制方案和补充血浆可促使恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dfe/6982510/96ab4ce35e37/CCR3-8-41-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dfe/6982510/96ab4ce35e37/CCR3-8-41-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dfe/6982510/96ab4ce35e37/CCR3-8-41-g001.jpg

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vWFpp/ADAMTS13 ratio is a useful marker of postliver transplantation thrombotic microangiopathy: A pediatric case report.血管性血友病因子裂解蛋白酶前体/ADAMTS13 比值是肝移植后血栓性微血管病的有用标志物：一例儿科病例报告。
Clin Case Rep. 2019 Dec 10;8(1):41-46. doi: 10.1002/ccr3.2495. eCollection 2020 Jan.
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本文引用的文献

1
Thrombotic microangiopathy after renal transplantation: Current insights in and recurrent disease.肾移植后血栓性微血管病：当前对新发及复发性疾病的认识
World J Transplant. 2018 Sep 10;8(5):122-141. doi: 10.5500/wjt.v8.i5.122.
2
ADAMTS13: origins, applications, and prospects.ADAMTS13：起源、应用及前景
Transfusion. 2018 Oct;58(10):2453-2462. doi: 10.1111/trf.14804. Epub 2018 Sep 12.
3
Von Willebrand Factor Deposition and ADAMTS-13 Consumption in Allograft Tissue of Thrombotic Microangiopathy-like Disorder After Living Donor Liver Transplantation: A Case Report.
活体肝移植后血栓性微血管病样疾病同种异体移植组织中血管性血友病因子沉积及ADAMTS-13消耗：一例报告
Transplant Proc. 2017 Sep;49(7):1596-1603. doi: 10.1016/j.transproceed.2017.02.047. Epub 2017 Jun 23.
4
Diagnostic approach to microangiopathic hemolytic disorders.微血管病性溶血性疾病的诊断方法
Int J Lab Hematol. 2017 May;39 Suppl 1:69-75. doi: 10.1111/ijlh.12671.
5
Update on ADAMTS13 and VWF in cardiovascular and hematological disorders.ADAMTS13与血管性血友病因子在心血管和血液系统疾病中的研究进展
Clin Chim Acta. 2016 Dec 1;463:109-118. doi: 10.1016/j.cca.2016.10.017. Epub 2016 Oct 14.
6
ADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpura.血栓性血小板减少性紫癜中的ADAMTS13和血管性血友病因子
Annu Rev Med. 2015;66:211-25. doi: 10.1146/annurev-med-061813-013241.
7
De novo thrombotic microangiopathy after non-renal solid organ transplantation.非肾实体器官移植后的新发血栓性微血管病
Blood Rev. 2014 Nov;28(6):269-79. doi: 10.1016/j.blre.2014.09.001. Epub 2014 Sep 20.
8
Syndromes of thrombotic microangiopathy.血栓性微血管病的综合征。
N Engl J Med. 2014 Aug 14;371(7):654-66. doi: 10.1056/NEJMra1312353.
9
Tacrolimus-induced thrombotic microangiopathy in orthotopic liver transplant patients: case series of four patients.他克莫司诱导的原位肝移植患者血栓性微血管病：4 例患者的病例系列。
Intern Med J. 2013 Mar;43(3):328-33. doi: 10.1111/imj.12048.
10
Behavior of ADAMTS13 and Von Willebrand factor levels in patients after living donor liver transplantation.肝移植术后患者 ADAMTS13 和血管性血友病因子水平的变化。
Thromb Res. 2013 Mar;131(3):225-9. doi: 10.1016/j.thromres.2012.12.002. Epub 2012 Dec 23.