Jesus-Ribeiro Joana, Bozorgi Alireza, Alkhaldi Modhi, Shaqfeh Mahmoud, Fernandez-Baca Vaca Guadalupe, Katirji Bashar
Neurology Department Coimbra University Hospital Center Coimbra Portugal.
Neurology Department University Hospitals Cleveland Medical Center and Case Western Reserve University School of Medicine Cleveland OH USA.
Clin Case Rep. 2019 Dec 12;8(1):61-64. doi: 10.1002/ccr3.2538. eCollection 2020 Jan.
Epilepsy should be suspected in patients with Stiff-person syndrome and new onset paroxysmal episodes. Musicogenic epilepsy may be a manifestation of anti-GAD-Ab spectrum, supporting an autoimmune workup in these patients. Appropriate treatment is not well established, and immunotherapy should be considered in patients with only partial response to antiepileptic drugs.
僵人综合征患者出现新发阵发性发作时应怀疑癫痫。音乐性癫痫可能是抗谷氨酸脱羧酶抗体谱的一种表现,这支持对这些患者进行自身免疫性检查。目前尚无确定的合适治疗方法,对抗癫痫药物仅有部分反应的患者应考虑免疫治疗。