SATB1 is a dopaminergic neuron-specific regulator of cellular senescence.
作者信息
Cancio-Bello Alexandra, Saez-Atienzar Sara
机构信息
Howard University College of Medicine, Washington, DC, USA.
Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
出版信息
Mov Disord. 2020 Feb;35(2):235. doi: 10.1002/mds.27978. Epub 2020 Jan 30.
Abstract
摘要
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Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline.清除衰老的神经胶质细胞可预防tau 依赖性病变和认知能力下降。
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Nat Genet. 2017 Oct;49(10):1511-1516. doi: 10.1038/ng.3955. Epub 2017 Sep 11.
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