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经黏膜下隧道内镜下隔肌切开术治疗Zenker憩室:两例病例报告

Zenker's diverticulum treated with submucosal tunneling endoscopic septum division surgery: Two case reports.

作者信息

Shen Baile, Jiang Haizhong, Li Zhuoya, Wang Zheng, Song Haojun, Ding Xiaoyun

机构信息

Medical School of Ningbo University.

Department of Gastroenterology, Ningbo First Hospital, Ningbo.

出版信息

Medicine (Baltimore). 2020 Jan;99(5):e18659. doi: 10.1097/MD.0000000000018659.

DOI:10.1097/MD.0000000000018659
PMID:32000372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7004738/
Abstract

INTRODUCTION

Zenker's diverticulum (ZD) refers to a pouch-like structure similar to the esophageal lumen formed from the herniation of the esophageal mucosa; this structure makes it difficult for food to pass through the esophagus to the stomach. The development of endoscopic technology has made minimally invasive surgical treatments for ZD possible.

PATIENT CONCERNS

A female 72-year-old patient was admitted to our hospital due to recurrent dysphagia for more than 5 years. A 62-year-old female patient underwent a gastroscopic examination due to recurrent dysphagia for 10 years and aggravated dysphagia accompanied by bad breath for 1 year.

DIAGNOSIS

A significant diverticulum with food residue at the entrance of the esophagus was found on gastroscopy in both cases.

INTERVENTIONS

After completing a relevant examination and excluding surgical contraindications, both patients underwent submucosal tunneling endoscopic septum division.

OUTCOMES

Both patients were discharged after symptoms alleviated on postoperative day 4. A 3-month follow-up gastroscopy showed the disappearance of the diverticulum and recovery of the esophageal anatomical structure. No symptom relapse was found at the 6-month follow-up assessment.

CONCLUSION

Submucosal tunneling endoscopic septum division has become the most common minimally invasive treatment option. It is efficient and safe for relieving symptomatic ZD in the short term.

摘要

引言

Zenker憩室(ZD)是指由食管黏膜疝出形成的类似食管腔的袋状结构;这种结构使食物难以通过食管进入胃。内镜技术的发展使ZD的微创手术治疗成为可能。

患者情况

一名72岁女性患者因反复吞咽困难5年以上入院。一名62岁女性患者因反复吞咽困难10年,且吞咽困难加重伴口臭1年接受胃镜检查。

诊断

两例患者胃镜检查均发现食管入口处有一个有食物残渣的巨大憩室。

干预措施

完成相关检查并排除手术禁忌证后,两名患者均接受了黏膜下隧道内镜憩室分隔术。

结果

两名患者均在术后第4天症状缓解后出院。术后3个月的胃镜检查显示憩室消失,食管解剖结构恢复。6个月随访评估未发现症状复发。

结论

黏膜下隧道内镜憩室分隔术已成为最常见的微创治疗选择。它在短期内缓解有症状的ZD方面高效且安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db8/7004738/2495957d971b/medi-99-e18659-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db8/7004738/5f815e172ced/medi-99-e18659-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db8/7004738/2495957d971b/medi-99-e18659-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db8/7004738/5f815e172ced/medi-99-e18659-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db8/7004738/2495957d971b/medi-99-e18659-g002.jpg

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本文引用的文献

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Pharyngoesophageal diverticula simulating thyroid nodules: An unusual occurrence with unique features.模拟甲状腺结节的咽食管憩室:一种具有独特特征的罕见情况。
Diagn Cytopathol. 2018 Feb;46(2):193-197. doi: 10.1002/dc.23817. Epub 2017 Sep 19.
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Submucosal Tunneling Endoscopic Septum Division: A Novel Technique for Treating Zenker's Diverticulum.
黏膜下隧道内镜下隔膜切开术:一种治疗Zenker憩室的新技术。
Gastroenterology. 2016 Dec;151(6):1071-1074. doi: 10.1053/j.gastro.2016.08.064. Epub 2016 Sep 21.
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Zenker's Diverticulum.Zenker's 憩室。
Clin Gastroenterol Hepatol. 2014 Nov;12(11):1773-82; quiz e111-2. doi: 10.1016/j.cgh.2013.09.016. Epub 2013 Sep 18.
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Zenker's diverticulum: the diagnostic power of ultrasound.泽克尔憩室:超声的诊断能力
Thyroid. 2010 Nov;20(11):1317-8. doi: 10.1089/thy.2010.0140. Epub 2010 Oct 9.
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Sonographic diagnosis features of Zenker diverticulum.超声诊断Zenker 憩室的特征。
Eur J Radiol. 2011 Nov;80(2):e13-9. doi: 10.1016/j.ejrad.2010.05.028. Epub 2010 Jun 23.
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Zenker's diverticulum presenting as a thyroid nodule.表现为甲状腺结节的Zenker憩室。
Thyroid. 2010 Apr;20(4):439-40. doi: 10.1089/thy.2009.0177.
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Exogenous lipoid pneumonia complicated with mycobacterium infection in a subject with Zenker diverticulum.
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