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澳大利亚队列中超级记忆超常老人的性别差异及相关因素

Gender Differences in Superior-memory SuperAgers and Associated Factors in an Australian Cohort.

作者信息

Maccora Janet, Peters Ruth, Anstey Kaarin J

机构信息

University of New South Wales, Sydney, Australia.

Neuroscience Research Australia (NeuRA), Sydney, New South Wales, Australia.

出版信息

J Appl Gerontol. 2021 Apr;40(4):433-442. doi: 10.1177/0733464820902943. Epub 2020 Jan 31.

Abstract

Despite expectations of deterioration in memory function with age, some older adults demonstrate superior memory performance and have been defined as SuperAgers. SuperAgers were identified in a population-based prospective cohort in Australia ( = 1,679; 49.4% female; mean age = 70.6 ±1.5 years) as participants who, over a 12-year period, consistently scored at or above the median of participants 40 years younger on recall tasks. Chi-square and tests and logistic regression models measured associations between risk factors and being a SuperAger. The prevalence of SuperAgers was higher in women (8.6%) than men (5.3%). Education was associated with being a SuperAger for women (adjusted odds ratio [OR] =1.13, 95% confidence interval [CI] = [1.01, 1.26]) and men (adjusted OR = 1.22, 95% CI = [1.05, 1.40]). Other associated factors were investigative activities and alcohol consumption for women and social activities and depressive symptoms for men. Adults over 60 can sustain superior memory recall; however, associated factors may vary between genders.

摘要

尽管人们预期记忆功能会随着年龄增长而衰退,但一些老年人却表现出卓越的记忆能力,他们被定义为“超级老人”。在澳大利亚一项基于人群的前瞻性队列研究中(n = 1679;49.4%为女性;平均年龄 = 70.6±1.5岁),“超级老人”被确定为在12年期间,在回忆任务中得分始终处于比其年轻40岁的参与者中位数及以上的参与者。卡方检验和t检验以及逻辑回归模型测量了风险因素与成为“超级老人”之间的关联。女性“超级老人”的患病率(8.6%)高于男性(5.3%)。教育与女性(调整后的优势比[OR] = 1.13,95%置信区间[CI] = [1.01, 1.26])和男性(调整后的OR = 1.22,95% CI = [1.05, 1.40])成为“超级老人”有关。其他相关因素在女性中是调查活动和饮酒,在男性中是社交活动和抑郁症状。60岁以上的成年人可以保持卓越的记忆回忆能力;然而,相关因素可能因性别而异。

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