National Health Service, Department of Mental Health, Psychiatric Service of Diagnosis and Treatment, Hospital 'G. Mazzini,' ASL 4 Teramo.
Department of Neurosciences and Imaging, Chair of Psychiatry, University 'G. D'Annunzio,' Chieti.
Int Clin Psychopharmacol. 2020 Mar;35(2):113-118. doi: 10.1097/YIC.0000000000000284.
Obsessive-compulsive disorder is often associated with schizophrenia and may represent a significant challenge in the treatment as this comorbidity may not respond properly to antipsychotic medication and usually require a pharmacological and psychotherapeutic add-on. In the present case report, we present the case of a 26-year-old male blue-collar subject who developed obsessive-compulsive disorder after a year of complete remission of schizophrenia symptoms under paliperidone long-acting injection that rapidly resolved after low-dosage cariprazine add-on. No adverse effects were reported due to cariprazine- paliperidone long-acting injection combination.
强迫症常与精神分裂症相关，且可能在治疗中构成重大挑战，因为这种合并症可能不能对抗精神病药物治疗产生适当的反应，通常需要药物和心理治疗的辅助。在本病例报告中，我们报告了 1 例 26 岁男性蓝领工人的病例，他在长效帕利哌酮注射治疗下精神分裂症症状完全缓解 1 年后出现强迫症，加用低剂量卡利拉嗪后迅速缓解。由于卡利拉嗪-长效帕利哌酮联合使用，未报告不良反应。
