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外科医生手术量对水泥固定和非水泥固定单髁膝关节置换术后相对翻修率的影响:来自英格兰、威尔士、北爱尔兰和马恩岛国家联合登记处的分析。

The Effect of Surgeon Caseload on the Relative Revision Rate of Cemented and Cementless Unicompartmental Knee Replacements: An Analysis from the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man.

机构信息

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom.

Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Southmead Hospital, Bristol, United Kingdom.

出版信息

J Bone Joint Surg Am. 2020 Apr 15;102(8):644-653. doi: 10.2106/JBJS.19.01060.

Abstract

BACKGROUND

Unicompartmental knee replacement (UKR) offers substantial benefits compared with total knee replacement (TKR) but is associated with higher revision rates. Data from registries suggest that revision rates for cementless UKR implants are lower than those for cemented implants. It is not known how much of this difference is due to the implant or to other factors, such as a greater proportion of high-volume surgeons using cementless implants. We aimed to determine the effect of surgeon caseload on the revision rate of matched cemented and cementless UKRs.

METHODS

From a group of 40,522 Oxford (Zimmer Biomet) UKR implants (30,814 cemented, 9,708 cementless) recorded in the National Joint Registry, 14,814 (7,407 cemented, 7,407 cementless) were propensity-score matched. Surgeons were categorized into 3 groups: low volume (<10 cases/year), medium volume (10 to <30 cases/year), and high volume (≥30 cases/year). The effect of caseload on the relative risk of revision was assessed with use of Cox regression.

RESULTS

The 10-year survival rates for unmatched cementless and cemented UKR implants were 93.3% (95% confidence interval [CI] = 89.8% to 95.7%) and 89.1% (95% CI = 88.6% to 89.6%), respectively, with the difference being significant (hazard ratio [HR] = 0.59; p < 0.001). Cementless UKR implants had a greater proportion of high-volume surgeon users than cemented implants (30.4% compared with 15.1%). Following matching, the 10-year survival rates were 93.2% (95% CI = 89.7% to 95.6%) and 90.2% (95% CI = 87.5% to 92.3%), which were still significantly different (HR = 0.76; p = 0.002). The 10-year survival rates for matched cementless and cemented UKR implants were 86.8% (95% CI = 73.6% to 93.7%) and 81.8% (95% CI = 73.0% to 88.0%) for low-volume surgeons, 94.3% (95% CI = 92.2% to 95.9%) and 92.5% (95% CI = 89.9% to 94.5%) for medium-volume surgeons, and 97.5% (95% CI = 96.5% to 98.2%) and 94.2% (95% CI = 90.8% to 96.4%) for high-volume surgeons. The revision rate for cementless implants was lower for surgeons in all 3 caseload groups (HR = 0.74, 0.79, 0.80, respectively).

CONCLUSIONS

Cementless fixation decreased the revision rate by about a quarter, whatever the surgeon caseload. Caseload had a profound effect on implant survival. Low-volume surgeons had a high revision rate with cemented or cementless fixation and therefore should consider either stopping or doing more UKR procedures. High-volume surgeons performing cementless UKR demonstrated a 10-year survival rate of 97.5%, which was similar to that reported in registries for the best-performing TKRs.

LEVEL OF EVIDENCE

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

与全膝关节置换术(TKR)相比,单髁膝关节置换术(UKR)具有显著优势,但翻修率更高。来自登记处的数据表明,非骨水泥固定 UKR 植入物的翻修率低于骨水泥固定植入物。尚不清楚这种差异有多少是由于植入物本身造成的,还有多少是由于其他因素造成的,例如使用非骨水泥固定植入物的高容量外科医生比例更高。我们旨在确定外科医生手术量对匹配的骨水泥固定和非骨水泥固定 UKR 的翻修率的影响。

方法

在全国关节登记处记录的 40522 例牛津(捷迈邦美)UKR 植入物(30814 例骨水泥固定,9708 例非骨水泥固定)中,我们对 14814 例(7407 例骨水泥固定,7407 例非骨水泥固定)进行了倾向评分匹配。将外科医生分为 3 组:低容量(<10 例/年)、中容量(10-<30 例/年)和高容量(≥30 例/年)。使用 Cox 回归评估手术量对相对风险的影响。

结果

未经匹配的非骨水泥固定和骨水泥固定 UKR 植入物的 10 年生存率分别为 93.3%(95%置信区间[CI]:89.8%至 95.7%)和 89.1%(95% CI:88.6%至 89.6%),差异有统计学意义(风险比[HR]:0.59;p<0.001)。非骨水泥固定 UKR 植入物的高容量外科医生使用者比例高于骨水泥固定植入物(30.4%比 15.1%)。匹配后,10 年生存率分别为 93.2%(95% CI:89.7%至 95.6%)和 90.2%(95% CI:87.5%至 92.3%),仍有显著差异(HR:0.76;p=0.002)。低容量外科医生匹配的非骨水泥固定和骨水泥固定 UKR 植入物的 10 年生存率分别为 86.8%(95% CI:73.6%至 93.7%)和 81.8%(95% CI:73.0%至 88.0%),中容量外科医生分别为 94.3%(95% CI:92.2%至 95.9%)和 92.5%(95% CI:89.9%至 94.5%),高容量外科医生分别为 97.5%(95% CI:96.5%至 98.2%)和 94.2%(95% CI:90.8%至 96.4%)。在所有 3 个手术量组中,非骨水泥固定的翻修率均较低(HR:0.74、0.79、0.80)。

结论

无论外科医生的手术量如何,非骨水泥固定都将翻修率降低了约四分之一。手术量对植入物的存活率有很大影响。低容量外科医生在使用骨水泥或非骨水泥固定时翻修率较高,因此应考虑停止或更多地进行 UKR 手术。高容量外科医生进行非骨水泥固定的 UKR 术后 10 年生存率为 97.5%,与登记处报告的最佳 TKR 相似。

证据水平

治疗性 III 级。欲了解完整的证据水平描述,请参阅作者说明。

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