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接受单髁膝关节置换术的患者比预计接受全膝关节置换术的患者具有更高的翻修风险,但死亡率更低:来自英格兰、威尔士、北爱尔兰和马恩岛国家关节登记处的数据。

Patients Receiving a Primary Unicompartmental Knee Replacement Have a Higher Risk of Revision but a Lower Risk of Mortality Than Predicted Had They Received a Total Knee Replacement: Data From the National Joint Registry for England, Wales, Northern Ireland, and the Isle of Man.

机构信息

Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Southmead Hospital, Bristol, United Kingdom.

Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Southmead Hospital, Bristol, United Kingdom; National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, United Kingdom.

出版信息

J Arthroplasty. 2021 Feb;36(2):471-477.e6. doi: 10.1016/j.arth.2020.08.063. Epub 2020 Sep 7.

DOI:10.1016/j.arth.2020.08.063
PMID:33011013
Abstract

BACKGROUND

To determine unicompartmental (UKR) and total knee replacement (TKR) revision rates, compare UKR revision rates with what they would have been had they received TKR instead, and assess subsequent re-revision and 90-day mortality rates.

METHODS

Using National Joint Registry data, we estimated UKR and TKR revision and mortality rates. Flexible parametric survival modeling (FPM) was used to model failure in TKR and make estimates for UKR. Kaplan-Meier estimates were used to compare cumulative re-revision for revised UKRs and TKRs.

RESULTS

Ten-year UKR revision rates were 2.5 times higher than expected from TKR, equivalent to 70 excess revisions/1000 cases within 10 years (5861 excess revisions in this cohort). Revision rates were 2.5 times higher for the highest quartile volume UKR surgeons compared to the same quartile for TKR and 3.9 times higher for the lowest quartiles respectively. Re-revision rates of revised TKRs (10 years = 17.5%, 95% confidence interval [CI] 16.4-18.7) were similar to revised UKRs (15.2%, 95% CI 13.4-17.1) and higher than revision rates following primary TKR (3.3%, 95% CI 3.1-3.5). Ninety-day mortality rates were lower after UKR compared with TKR (0.08% vs 0.33%) and lower than predicted had UKR patients received a TKR (0.18%), equivalent to 1 fewer death per 1000 cases.

CONCLUSION

UKR revision rates were substantially higher than TKR even when demographics and caseload differences were accounted for; however, fewer deaths occur after UKR. This should be considered when forming treatment guidelines and commissioning services. Re-revision rates were similar between revised UKRs and TKRs, but considerably higher than for primary TKR, therefore UKR cannot be considered an intermediate procedure.

摘要

背景

为了确定单髁膝关节置换术(UKR)和全膝关节置换术(TKR)的翻修率,比较 UKR 的翻修率与如果接受 TKR 治疗时的预期翻修率,并评估随后的再次翻修和 90 天死亡率。

方法

使用国家关节登记处的数据,我们估计了 UKR 和 TKR 的翻修和死亡率。使用灵活参数生存模型(FPM)对 TKR 的失败进行建模,并对 UKR 进行估计。使用 Kaplan-Meier 估计来比较 UKR 和 TKR 修订后的累积再次修订率。

结果

10 年 UKR 翻修率比 TKR 预期高出 2.5 倍,相当于 10 年内每 1000 例中有 70 例额外翻修(本队列中 5861 例额外翻修)。最高四分位 UKR 外科医生的翻修率比同一四分位 TKR 的翻修率高 2.5 倍,而最低四分位的翻修率高 3.9 倍。修订后的 TKR(10 年=17.5%,95%置信区间[CI] 16.4-18.7)的再次翻修率与修订后的 UKR(15.2%,95%CI 13.4-17.1)相似,高于初次 TKR 的翻修率(3.3%,95%CI 3.1-3.5)。与 TKR 相比,UKR 的 90 天死亡率较低(0.08%比 0.33%),低于 UKR 患者接受 TKR 时的预期死亡率(0.18%),相当于每 1000 例减少 1 例死亡。

结论

即使考虑到人口统计学和病例量的差异,UKR 的翻修率也明显高于 TKR;然而,UKR 后死亡率较低。在制定治疗指南和委托服务时应考虑到这一点。修订后的 UKR 和 TKR 的再次翻修率相似,但明显高于初次 TKR,因此 UKR 不能被视为中间程序。

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