Department of Surgery, Macerata Hospital, Macerata, Italy.
Curr Opin Crit Care. 2020 Apr;26(2):205-211. doi: 10.1097/MCC.0000000000000696.
The review focuses on the evaluation and management of abdominal sepsis.
A multitude of surgical approaches towards abdominal sepsis are practized in the world and may be associated with significant morbidity and mortality rates. Despite decades of sepsis research, no specific therapies for sepsis have emerged. Without specific therapies, the management of abdominal sepsis is based on the control of the infection and organ support.
Early clinical diagnosis, adequate source control to stop ongoing contamination, appropriate antibiotic therapy dictated by patient and infection risk factors, and prompt resuscitation are the cornerstones of its management.
本文重点介绍了腹部脓毒症的评估和处理。
目前全世界有许多种针对腹部脓毒症的手术方法,但这些方法可能会导致较高的发病率和死亡率。尽管脓毒症的研究已经进行了几十年,但仍未出现针对脓毒症的特定疗法。由于没有特效疗法,因此腹部脓毒症的处理主要基于感染的控制和器官支持。
其处理的关键是早期临床诊断、充分的源头控制以停止持续污染、根据患者和感染危险因素选择合适的抗生素治疗,以及及时复苏。