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一项关于外科医生在择期结直肠手术后使用泻药的偏好和实践的全球调查。

A global survey of surgeons' preferences and practice with regard to laxative use after elective colorectal surgery.

机构信息

Colorectal Unit, Department of Surgery, Royal Adelaide Hospital, Port Road, Adelaide, SA, 5000, Australia.

Discipline of Surgery, Faculty of Health and Medical Science, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.

出版信息

Int J Colorectal Dis. 2020 Apr;35(4):759-763. doi: 10.1007/s00384-020-03521-1. Epub 2020 Jan 31.

Abstract

PURPOSE

The role of laxatives after elective colorectal surgery is unclear, resulting in heterogenous guidelines and variability in clinical practice. This study aimed to gauge surgeons' preferences and practice with regard to laxative use following elective colorectal surgery.

METHODS

A short one-minute anonymous web-based questionnaire designed in English and Chinese (Mandarin) using the Research Electronic Data Capture application (REDCap) was distributed to member surgeons of every identifiable international colorectal specialist society via email communication, physical newsletters and social media channels. Frequency of laxative use after elective colorectal surgery, type of laxative used, and, if not used, the reasons for not using laxatives were collected.

RESULTS

A total of 852 surgeons, representing 28 surgical societies completed the survey: 80% were colorectal surgeons and 20% were general surgeons with colorectal interest. Twenty-seven percent of the respondents routinely prescribed laxatives after colorectal surgery. There was wide variation in the type of laxatives used, with magnesium-based laxatives (42%), macrogol (Movicol, 36%) and lactulose (Duphalac, 22%) being the most common. Geographical location was correlated with choice of laxative. Those not routinely using laxatives stated the reasons as being no evidence for benefit (48%), potential of adverse events (24%), more than one reason (21%) and other (7%). The majority (93%) non-users would consider using laxatives if better evidence was available.

CONCLUSION

Most surgeons do not routinely prescribe laxatives after elective colorectal surgery due to lack of evidence. Amongst those surgeons who do use them, there is wide variability in the type of laxatives used.

摘要

目的

择期结直肠手术后使用泻药的作用尚不清楚,导致指南存在差异,临床实践也存在差异。本研究旨在评估外科医生在择期结直肠手术后使用泻药的偏好和实践。

方法

使用 Research Electronic Data Capture 应用程序(REDCap)以英文和中文(普通话)设计了一个简短的一分钟匿名网络问卷,通过电子邮件、纸质通讯和社交媒体渠道分发给每个可识别的国际结直肠专家协会的会员外科医生。收集择期结直肠手术后使用泻药的频率、使用的泻药类型,如果未使用,不使用泻药的原因。

结果

共有 852 名外科医生代表 28 个外科协会完成了这项调查:80%是结直肠外科医生,20%是有结直肠兴趣的普通外科医生。27%的受访者常规在结直肠手术后开具泻药。使用的泻药类型差异很大,其中镁基泻药(42%)、聚乙二醇(Movicol,36%)和乳果糖(Duphalac,22%)最为常见。地理位置与泻药的选择有关。那些不常规使用泻药的人表示,没有益处的证据(48%)、潜在的不良事件(24%)、超过一个原因(21%)和其他原因(7%)是不使用的原因。如果有更好的证据,大多数非使用者(93%)会考虑使用泻药。

结论

由于缺乏证据,大多数外科医生在择期结直肠手术后不常规开泻药。在那些使用泻药的外科医生中,使用的泻药类型差异很大。

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