Sumathi T, Manivasagam T, Thenmozhi A Justin
Department of Medical Biochemistry, Dr. ALMPGIBMS, University of Madras, Chennai, Tamil Nadu, India.
Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Chidambaram, Tamil Nadu, India.
Adv Neurobiol. 2020;24:469-479. doi: 10.1007/978-3-030-30402-7_14.
Autism spectrum disorder (ASD) is an inherited neurodevelopmental disorder of social communication and restricted, repetitive behaviors. Much remains unknown about their mechanisms of action and physiological effects. In recent years, there has been a growing interest in nutritional diets, which can be used as a form of therapeutic intervention for ASD with a recent increase in the research being carried out in this field. Selective nutrition therapy for ASD and brain function shows improvement in behavioral changes and reduction in malnutrition seemingly associated with the allergies or food intolerances to gluten. Therefore, a gluten-free diet has yielded positive outcomes giving hope in developing therapy for ASD.
自闭症谱系障碍（ASD）是一种遗传性神经发育障碍，表现为社交沟通障碍以及受限的重复行为。关于其作用机制和生理效应，仍有许多未知之处。近年来，人们对营养饮食的兴趣日益浓厚，营养饮食可作为ASD的一种治疗干预形式，且该领域的研究近来有所增加。针对ASD和脑功能的选择性营养疗法显示出行为改变有所改善，与麸质过敏或食物不耐受相关的营养不良情况有所减少。因此，无麸质饮食已产生积极效果，为开发ASD治疗方法带来了希望。
