认知储备可减弱胃肠道疾病与随后执行功能下降之间的关系。
Cognitive Reserve Attenuates the Relation between Gastrointestinal Diseases and Subsequent Decline in Executive Functioning.
机构信息
Department of Psychology, University of Geneva, Geneva, Switzerland,
Center for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, Geneva, Switzerland,
出版信息
Dement Geriatr Cogn Disord. 2019;48(3-4):215-218. doi: 10.1159/000505617. Epub 2020 Jan 31.
AIMS
We investigated whether the longitudinal relationship between gastrointestinal diseases and subsequent decline in executive functioning over 6 years differed by cognitive reserve.
METHODS
We analyzed longitudinal data from 897 older adults (mean age 74.33 years) tested on TMT parts A and B in two waves 6 years apart. Participants reported information on education, occupation, leisure activity engagement, and gastrointestinal diseases.
RESULTS
There was a significant interaction of gastrointestinal diseases with leisure activity engagement on latent change in executive functioning. Specifically, only for individuals with low (but not those with high) leisure activity engagement, gastrointestinal diseases significantly predicted a steeper subsequent decline in executive functioning across 6 years (i.e., increases in TMT completion time).
CONCLUSION
Cognitive reserve may attenuate the detrimental influences of gastrointestinal diseases on subsequent decline in executive functioning.
目的
我们研究了胃肠道疾病与 6 年内执行功能下降之间的纵向关系是否因认知储备而异。
方法
我们分析了来自 897 名年龄在 74.33 岁的老年人的纵向数据，这些老年人在两次相隔 6 年的测试中完成了 TMT 部分 A 和 B。参与者报告了教育、职业、休闲活动参与度以及胃肠道疾病的信息。
结果
胃肠道疾病与休闲活动参与度在执行功能的潜在变化上存在显著的交互作用。具体来说，只有在休闲活动参与度低（而不是高）的个体中，胃肠道疾病才显著预测了 6 年内执行功能的更陡峭下降（即 TMT 完成时间的增加）。
结论
认知储备可能会减轻胃肠道疾病对执行功能后续下降的不利影响。
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