Wu W J, Liang Y, Cao P, Zhang X K, Zheng T, Qiu J R
Department of Orthopedics, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Zhonghua Yi Xue Za Zhi. 2020 Jan 21;100(3):192-196. doi: 10.3760/cma.j.issn.0376-2491.2020.03.007.
To evaluate the effect of minimally invasive lateral lumbar interbody fusion (LLIF/OLIF) on the sagittal balance of adult degenerative scoliosis. From January 2014 to June 2017, a total of 23 patients with degenerative scoliosis underwent staged minimally invasive surgery in Shanghai Ruijin Hospital. All patients were implanted with LLIF or OLIF cage from the lateral approach first, and was followed by the posterior percutaneous pedicle screw fixation or pedicle screw fixation via Wiltse approach. If the sagittal deformity correction was not satisfactory after the first surgery, a posterior osteotomy can be performed during the second stage operation. A biplanar X-ray of the whole spine was taken with the EOS imaging system before and after surgery. The EOS software was used to measure and evaluate the patient's sagittal balance parameters including pelvic incidence (PI), pelvic tilt (PT), lumbar lordosis (LL), the sagittal vertical axis (SVA) and the coronal Cobb angle. The visual analogue scale (VAS) score for low back pain, the Oswestry Disability Index (ODI) score were evaluated before and after surgery. Paired test or repeated measures ANOVA was used to compare the data before and after surgery. There were 6 males and 17 females with a mean age of (72±4) years (62-79 years). Nine patients were treated with LLIF and 14 patients with OLIF. Sixteen cases were implanted with three cages, five with two cages and two with four cages. The mean follow-up period was 24.2 months (15-42 months). After the first operation, the Cobb angle of the patient was significantly improved (18°±7° vs 33°±8°, 13.2, 0.01). All the parameters for sagittal balance, including PI-LL (20°±8° vs 31°±8(o)), SVA ((5.3±2.0) cm vs (8.2±3.5) cm), PT (16°±6° vs 23°±4°) were all significantly improved as well (6.8, 4.5, 9.0, ALL 0.01). At the last follow-up, the VAS score of low back pain (3.4±1.1 vs 6.3±1.0) and ODI scores (27.3%±3.0% vs 47.1%±5.9%) were also significantly improved (11.3, 17.8, both 0.01). No major complications occurred in this group. Minimally invasive LLIF/OLIF can significantly improve the coronal and sagittal balance of adult degenerative scoliosis. Staged minimally invasive surgery can significantly alleviate pain and improve function in these patients.
评估微创外侧腰椎椎间融合术(LLIF/OLIF)对成人退变性脊柱侧凸矢状面平衡的影响。2014年1月至2017年6月,共有23例退变性脊柱侧凸患者在上海瑞金医院接受了分期微创手术。所有患者均首先从外侧入路植入LLIF或OLIF椎间融合器,随后行经皮后路椎弓根螺钉固定或经Wiltse入路椎弓根螺钉固定。如果首次手术后矢状面畸形矫正不满意,可在二期手术中进行后路截骨术。手术前后使用EOS成像系统拍摄全脊柱双平面X线片。使用EOS软件测量和评估患者的矢状面平衡参数,包括骨盆入射角(PI)、骨盆倾斜角(PT)、腰椎前凸(LL)、矢状垂直轴(SVA)和冠状面Cobb角。评估手术前后的下腰痛视觉模拟量表(VAS)评分和Oswestry功能障碍指数(ODI)评分。采用配对检验或重复测量方差分析比较手术前后的数据。患者中男性6例,女性17例,平均年龄(72±4)岁(62 - 79岁)。9例患者接受LLIF治疗,14例患者接受OLIF治疗。16例植入3个椎间融合器,5例植入2个椎间融合器,2例植入4个椎间融合器。平均随访时间为24.2个月(15 - 42个月)。首次手术后,患者的Cobb角显著改善(18°±7° vs 33°±8°,P = 13.2,0.01)。所有矢状面平衡参数,包括PI - LL(20°±8° vs 31°±8°)、SVA((5.3±2.0)cm vs (8.2±3.5)cm)、PT(16°±6° vs 23°±4°)也均显著改善(P = 6.8、4.5、9.0,均为0.01)。在末次随访时,下腰痛VAS评分(3.4±1.1 vs 6.3±1.0)和ODI评分(27.3%±3.0% vs 当47.1%±5.9%)也显著改善(P = 11.3、17.8,均为0.01)。该组未发生重大并发症。微创LLIF/OLIF可显著改善成人退变性脊柱侧凸的冠状面和矢状面平衡。分期微创手术可显著减轻这些患者的疼痛并改善功能。