肺癌病理学：当前概念。
Lung Cancer Pathology: Current Concepts.
机构信息
Thoracic Pathology, Department of Pathology, Memorial Sloan Kettering Cancer Center, Room A525, 1275 York Avenue, New York, NY 10065, USA.
出版信息
Clin Chest Med. 2020 Mar;41(1):67-85. doi: 10.1016/j.ccm.2019.11.001. Epub 2020 Jan 2.
Lung cancer can be diagnosed based on histologic biopsy or cytologic specimens. The 2015 World Health Organization Classification of Lung Tumors addressed the diagnosis of lung cancer in resection specimens and in small biopsies and cytology specimens. For these small specimens, diagnostic terms and criteria are recommended. Targetable mutations such as EGFR and ALK rearrangements emphasize the importance of managing these small specimens for molecular testing.
肺癌可以基于组织学活检或细胞学标本进行诊断。2015 年世界卫生组织肺癌肿瘤分类针对的是切除标本以及小活检和细胞学标本中的肺癌诊断。对于这些小标本，推荐使用诊断术语和标准。可靶向的突变，如 EGFR 和 ALK 重排，强调了对这些小标本进行分子检测的重要性。
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